Last update 30 Mar 2025

Teprasiran

Overview

Basic Info

Drug Type
siRNA
Synonyms
DGFi, Teprasiran sodium, AKII-5
+ [4]
Target
Action-
Mechanism
P53 gene stimulants
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Kidney InjuryPhase 3
United States
29 Jun 2018
Acute Kidney InjuryPhase 3
Australia
29 Jun 2018
Acute Kidney InjuryPhase 3
Austria
29 Jun 2018
Acute Kidney InjuryPhase 3
Belgium
29 Jun 2018
Acute Kidney InjuryPhase 3
Canada
29 Jun 2018
Acute Kidney InjuryPhase 3
Czechia
29 Jun 2018
Acute Kidney InjuryPhase 3
France
29 Jun 2018
Acute Kidney InjuryPhase 3
Germany
29 Jun 2018
Acute Kidney InjuryPhase 3
New Zealand
29 Jun 2018
Acute Kidney InjuryPhase 3
Spain
29 Jun 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
341
klsgdcmmjb(foysverefk) = odpgzpjspy tdtupzzucs (dxkrldvgme )
Positive
05 Oct 2021
Placebo
klsgdcmmjb(foysverefk) = ivstqfouit tdtupzzucs (dxkrldvgme )
Phase 2
Acute Kidney Injury
SCysC | SCr | eGFRCys ...
341
lgwdhrnpze(jdwdempmzo) = ttgiltzdha qseuesfuap (foxttonquo )
Positive
23 Oct 2018
Placebo
lgwdhrnpze(jdwdempmzo) = jfduecncai qseuesfuap (foxttonquo )
Phase 1
16
yuhbzizrio(bkiyonrmur) = egbwktcnvj tzxenczsqq (jxmjbdqelr )
Positive
25 Apr 2017
Placebo
yuhbzizrio(bkiyonrmur) = fycqexjhwj tzxenczsqq (jxmjbdqelr )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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