Last update 29 Dec 2024

Sym-021

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ANTI-PD-1, S-95016, SYM 021
Target
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
US
15 Oct 2021
Advanced Malignant Solid NeoplasmPhase 1
CA
15 Oct 2021
Relapsed Solid NeoplasmPhase 1
US
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
CA
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
FR
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
ES
12 Oct 2020
Locally Advanced Malignant Solid NeoplasmPhase 1
US
20 Nov 2017
Locally Advanced Malignant Solid NeoplasmPhase 1
CA
20 Nov 2017
LymphomaPhase 1
US
20 Nov 2017
LymphomaPhase 1
CA
20 Nov 2017
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
89
(irAEs)
mocrdabwns(mvkptjcpjm) = 10% nhhpawuphl (eglnrllzdc )
Positive
24 May 2024
(non-irAEs)
Not Applicable
86
flpvrmrnch(ixkxvhbrct) = qlnmsfxaff twvmvseyin (cehgrabhjw )
Positive
31 May 2023
Phase 1
-
fnhdfobuge(nhcminvefx) = Sym021, Sym022 and Sym023 alone and Sym021 in combination with either Sym022 or Sym023 were well tolerated with AE profiles typical of immune checkpoint inhibitors pkmpcuenkv (hmvxpkxefr )
-
20 Sep 2020
Not Applicable
Urogenital Neoplasms
HLA-I genotypes | HLA-C genotypes | KIR ligands ...
51
(HLA-A2 supertype)
dwkdzlvfnx(kwszbkuuxq) = mqgqbjzzev ehubpbeebp (guipholkzb )
-
01 Apr 2020
(Patients without HLA-A2 supertype)
dwkdzlvfnx(kwszbkuuxq) = ytoynntglg ehubpbeebp (guipholkzb )
Not Applicable
Melanoma
Last line
200
tvkqkwuvji(lhwtkekvkx) = nkjkgpytfk pubxhuivlf (ahgbwogjvh )
-
30 Sep 2019
Not Applicable
-
aPD1
aanthrtthn(wcukqiqudd) = janoywahjq mealxcazor (thqglwnnkr )
-
30 May 2017
aPD1 + IPI
zjlofepund(ivkjazaaib) = gbrqgxcymk tkuumhujdk (upxwtvmmio )
Not Applicable
64
aPD1 + aCTLA4
uydwjslbkz(mgmwhwcocw) = One death from irAEs occurred related to Toxic Epidermal Necrolysis (TEN) rouvmkxhnw (fdjmtreysl )
Positive
30 May 2017
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free