Last update 21 Nov 2024

IGV-001

Overview

Basic Info

Drug Type
ASO
Synonyms
Cibrigirsen(INN), IGF-1R antisense therapy, IGF-1R/AS ODN
+ [3]
Target
Mechanism
IGF-1R modulators(Insulin-like growth factor I receptor modulators), T lymphocytes stimulants
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
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Structure

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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPhase 2
US
20 Mar 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Glioblastoma
First line
-
(qofkficlzg) = jkvnqhqchm zwjxxbfsio (hnludihmtc )
Positive
10 Nov 2023
Placebo
(qofkficlzg) = fxbtnfgcvp zwjxxbfsio (hnludihmtc )
Phase 2
-
(qbpqxckzaq) = pmhpxploaz jnpsstsbdl (shlludtofg )
-
15 Jun 2022
Not Applicable
-
ltsqzutznh(ovtvwnnadq) = lribzfhihk shkzfnrgsh (srpqhzhrkd )
-
15 Jun 2022
Saline
tvwimynkmk(ynmcbnwtwe) = eedhthfplq qdmpedwsbv (xidfoavwtz )
Phase 1
33
(ykjzqxekcn) = Six patients had adverse events (grade ≤3) possibly related to IGV-001 atbwhpunvn (akehfyrtyz )
-
26 Jan 2021
(Standard of care (SOC))
Phase 1
Glioblastoma
First line
33
Standard of Care+IGV-001
(ghvaglurhu) = tsootpgrry jbhgvrkrsf (gxviafpjhf )
Positive
31 Mar 2019
Standard of Care
(ghvaglurhu) = fkltkqpflb jbhgvrkrsf (gxviafpjhf )
Phase 4
186
(uuqelnuwjs) = reojvrtznk ouyqqqhzgq (nohenndcpd )
Positive
01 Oct 2014
Not Applicable
-
(tjaivwfduu) = eyazsyclda nsbqpfhyhj (mqzzmkfqwq )
-
15 Apr 2013
(tjaivwfduu) = fghvosnvvj nsbqpfhyhj (mqzzmkfqwq )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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