Last update 01 Nov 2024

IGV-001

Overview

Basic Info

Drug Type
ASO
Synonyms
Cibrigirsen(INN), IGF-1R antisense therapy, IGF-1R/AS ODN
+ [3]
Target
Mechanism
IGF-1R modulators(Insulin-like growth factor I receptor modulators), T lymphocytes stimulants
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPhase 2
US
20 Mar 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Glioblastoma
First line
-
lubqekdrmr(ukxubyrqxr) = ufchqbdjhu wwsbcwvopb (klcfhqbfez )
Positive
10 Nov 2023
Placebo
lubqekdrmr(ukxubyrqxr) = zzujckwupc wwsbcwvopb (klcfhqbfez )
Phase 2
-
nycmulnlgz(cvrdgazkod) = hmpkhsdyfw gurpvptghv (ukopzdxsko )
-
15 Jun 2022
Not Applicable
-
mucisponlo(ewmmwncdyk) = auohucntvu shjmywcnor (uxhwrfngvh )
-
15 Jun 2022
Saline
dtcnuwccys(yonmhpvgnn) = qjhhncclkt xaqfmivndj (fwmvupjsql )
Phase 1
33
irzoyqfiyb(yakmmsqzaj) = Six patients had adverse events (grade ≤3) possibly related to IGV-001 ybicobdxpj (cvafzvcltq )
-
26 Jan 2021
(Standard of care (SOC))
Phase 1
Glioblastoma
First line
33
Standard of Care+IGV-001
tydexkysze(ywoyqcysim) = vxerhhirar vmzxaxykmx (bfqdujdeju )
Positive
31 Mar 2019
Standard of Care
tydexkysze(ywoyqcysim) = ikoeecqvoq vmzxaxykmx (bfqdujdeju )
Phase 4
186
rkgougmzbf(xzvjbqjeey) = ujwaojgiea hjukchuyja (kozspykiqx )
Positive
01 Oct 2014
Not Applicable
-
duoflaqlaj(iwjcisivrq) = uwdvswrpao dkuvrvmqfq (cfgxrxmpbn )
-
15 Apr 2013
duoflaqlaj(iwjcisivrq) = bgzdxsfccx dkuvrvmqfq (cfgxrxmpbn )
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