Last update 01 Nov 2024

Lumrotatug

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
Mechanism
CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Plasma cell myeloma refractoryPhase 2-28 Feb 2024
Multiple MyelomaPhase 2
CN
17 Jan 2024
Systemic Lupus ErythematosusPhase 2
CN
14 Oct 2022
Purpura, Thrombocytopenic, IdiopathicPhase 2
CN
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
22
(wcdmwobnug) = The most common that occurred during the study were infusion-related reaction (in 32% of the patients) and upper respiratory tract infection (in 32%). zcwaeiqgik (ptqbkclbgy )
Positive
19 Jun 2024
Phase 2
21
fqncdnivri(ioamisyvsg) = 6 (6/21, 28.6%) had an infusion-related reaction (IRR) at the first dose but none at subsequent doses. The severity of IRR was grade 1 or 2 (according to CTCAE version 5.0) mnkaxgcork (fugqnridpu )
Positive
09 Dec 2023
Phase 1
34
ebqqzmmkqg(wdncneupis) = Grade 3 or higher treatment-emergent adverse events (TEAEs) were reported in 15/34 (44.1%) pts (8 [23.5%] were considered drug related); there were no grade 5 TEAEs zolyrwsdsv (wsapubhdhn )
-
08 Jun 2023
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Approval

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Regulation

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