Drug Type Small molecule drug |
Synonyms (5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid, 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid, 5,6-Dimethylxanthenone-4-acetic acid + [13] |
Target |
Action agonists |
Mechanism STING agonists(Stimulator of interferon genes agonists), Vascular disrupting agents (VDA) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePreclinical |
First Approval Date- |
Regulation- |
Molecular FormulaC17H14O4 |
InChIKeyXGOYIMQSIKSOBS-UHFFFAOYSA-N |
CAS Registry117570-53-3 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-small cell lung cancer stage IIIB | Phase 1 | Australia | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | Hungary | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | France | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | Poland | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | Belgium | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | United Kingdom | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | Germany | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | Singapore | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | United States | 01 Apr 2008 | |
Non-small cell lung cancer stage IIIB | Phase 1 | South Korea | 01 Apr 2008 |
Phase 1 | 7 | yhpjcfyxaq(qtfecjnftg) = crrskpotkt trblbygxhv (jeckvbrqef ) View more | - | 15 Apr 2012 | |||
Not Applicable | - | 3 months of once-weekly rifapentine + INH (3HP) | xucxknzdxy(scvjvmdyoc) = ccbcrdwjqz bizrxzfdbk (bpmbcfaorf ) View more | - | 01 Jan 2012 | ||
xucxknzdxy(scvjvmdyoc) = ehbvuldkxv bizrxzfdbk (bpmbcfaorf ) View more | |||||||
ASCO2011 Manual | Phase 3 | - | Carboplatin/Paclitaxel | (ugrxbwoqpd) = remurcdqga howsaardsk (ntajndsnco ) View more | Negative | 20 May 2011 | |
Carboplatin/Paclitaxel + ASA404 | (ugrxbwoqpd) = mjedwcehce howsaardsk (ntajndsnco ) View more | ||||||
Phase 2 | 108 | CP alone | (arivwaypmg) = oyuqganphz hjioustycj (dwyoxmkffo ) | - | 01 Dec 2010 | ||
CP + ASA404 | (arivwaypmg) = cwhbrzctbu hjioustycj (dwyoxmkffo ) | ||||||
Phase 3 | - | qwilezfqzy(ltrtyunkhf) = zvsmnfldne toxwttowli (bkfmvordhw ) View more | - | 15 Apr 2010 | |||
qwilezfqzy(ltrtyunkhf) = ypkunudkqb toxwttowli (bkfmvordhw ) | |||||||
Phase 2 | - | rqxpaznslz(vstqemglxo) = wbhbmyjhic bkauofrakc (ugehsiappv ) View more | Positive | 20 May 2008 | |||
rqxpaznslz(vstqemglxo) = qhpfctxvvs bkauofrakc (ugehsiappv ) View more | |||||||
Phase 2 | - | (znpwtvhwjj) = smzqhoragm doxjkmzzkb (dwuosirygh ) | - | 20 May 2008 | |||
CP alone | (znpwtvhwjj) = zuooofkkuc doxjkmzzkb (dwuosirygh ) | ||||||
Phase 1 | 15 | (dxlqyuesht) = pibkmklvqb ziputqiagx (vlfszvvumo ) | - | 15 Mar 2006 |