Delving into the Latest Updates on Amniotic Fluid Eye Drops(University of Utah) with Synapse

Overview

Basic Info

Drug Type

Biological products

Synonyms-

Target-

Mechanism-

Therapeutic Areas

Immune System DiseasesOther Diseases

Active Indication

Chronic graft-versus-host disease

Inactive Indication-

Originator Organization

University of Utah

Active Organization

University of Utah

Inactive Organization-

Drug Highest PhasePhase 1/2

First Approval Date-

Regulation-

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A comparative study of Solcoseryl eye drops versus Vitasic eye drops has been carried out under controlled conditions (randomized and double-blind) on a total of 94 patients. 52 had corneal erosion, 30 had dry eye syndrome, 8 cases could not be evaluated. In addition, 2 eyes with photophthalmia were treated with Vitasic and 2 showing keratitis with Solcoseryl. There were no adverse reactions other than 2 instances of stinging with Solcoseryl and 1 case of severe irritation after Vitasic. The patients were examined on days 0, 1, 3 and 7. Results showed a consistent superiority of Solcoseryl eye drops in respect to speed of healing of corneal erosions and moistening of the cornea in the 'dry eye' syndrome which reached statistical significance in some parameters.

100 Deals associated with Amniotic Fluid Eye Drops(University of Utah)

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Chronic graft-versus-host disease	Phase 2	US	University of Utah	20 Dec 2019

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Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT03298815 (ASH2023)	Phase 2	Chronic graft-versus-host disease	15	Processed Amniotic Fluid (pAF) Drops (Processed Amniotic Fluid (pAF))	(oemmxifsup) = dxwnpefsqp whiynqlbgg (bmomqipiwl )	Positive	10 Dec 2023
				Processed Amniotic Fluid (pAF) Drops (Saline treatment (placebo))	(oemmxifsup) = vbszpqhzmr whiynqlbgg (bmomqipiwl )