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Last update 26 Dec 2025
AMT-116(Multitude Therapeutics)
Last update 26 Dec 2025
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms- |
Target |
Action inhibitors |
Mechanism CD44 inhibitors(CD44 antigen inhibitors), Tubulin inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC11H22N4O4 |
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N |
CAS Registry159858-33-0 |
View All Structures (2)
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Related
2
Clinical Trials associated with AMT-116(Multitude Therapeutics)NCT06782334
Phase 1/2 Study of AMT-116 in Patients with Advanced Solid Tumors
NCT05725291
First-in-Human, Phase 1 Study of AMT-116 in Patients With Advanced Solid Tumors
100 Clinical Results associated with AMT-116(Multitude Therapeutics)
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100 Translational Medicine associated with AMT-116(Multitude Therapeutics)
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100 Patents (Medical) associated with AMT-116(Multitude Therapeutics)
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100 Deals associated with AMT-116(Multitude Therapeutics)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 24 Apr 2024 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1/2 | 164 | (all doses) | jnfkwswjnz(mnzyrmccwk) = yyteufwihp lrknhrmfdk (xtyiakuvqg ) View more | Positive | 17 Oct 2025 | ||
(≥3 mg/kg) | jnfkwswjnz(qwagzafrnr) = dcmnpmixgj zfdtgkhdbl (bsupuuleao ) View more | ||||||
Phase 1/2 | 102 | weqkyumjfw(akcybosyma) = opxuyvrphr bpuamyljxy (nuyqpoyxyt ) View more | Positive | 17 Oct 2025 | |||
(EGFR wild-type NSCLC) | nzlbgklvae(phceppeyoh) = okrrjwjuco oczippvdbp (fywgfnubjz ) View more | ||||||
Phase 1 | 8 | AMT-116 3 mg/kg | yvifebybsj(wqdlefewru) = No DLT events were observed kdcpdqzhwo (aejqqubcnp ) View more | Positive | 24 May 2024 |
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Translational Medicine
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Deal
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Core Patent
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Clinical Trial
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Approval
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Biosimilar
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Regulation
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