Last update 26 Apr 2025

Nabilone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nabilone (USAN/INN), CPD 109514, CPD-109514
+ [3]
Target
Action
agonists
Mechanism
CB agonists(Cannabinoid receptor agonists)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date
United States (26 Dec 1985),
Regulation-
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Structure/Sequence

Molecular FormulaC24H36O3
InChIKeyGECBBEABIDMGGL-PVIFGLDDSA-N
CAS Registry51022-71-0

External Link

KEGGWikiATCDrug Bank
D05099Nabilone

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chemotherapy-induced nausea and vomiting
United States
26 Dec 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AgitationPhase 3
Canada
01 Feb 2021
Alzheimer DiseasePhase 3
Canada
01 Feb 2021
Aphasia, Primary ProgressivePhase 2
Canada
07 Mar 2023
Aphasia, Primary ProgressivePhase 2
Canada
07 Mar 2023
Frontotemporal DementiaPhase 2
Canada
07 Mar 2023
Frontotemporal DementiaPhase 2
Canada
07 Mar 2023
NeuralgiaPhase 2
Canada
01 Jan 2009
Phantom LimbPhase 2
Canada
01 Jan 2009
Muscle SpasticityPhase 2
Canada
01 Jul 2007
Spinal Cord InjuriesPhase 2
Canada
01 Jul 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
48
(Treatment Group)
gkvrusojpy(rtnnrkpgiw) = bmejgprqkk fsefdasovj (ssszlduswx, bpfzxkmbgn - ckgeukcxoy)
-
02 Mar 2021
Placebo
(Placebo Group)
gkvrusojpy(rtnnrkpgiw) = uzrbyyauxy fsefdasovj (ssszlduswx, pcbifrqezw - hutzcrmdqm)
Phase 3
22
emnyrvtxhy = ocrhjbzjza hlcobvegwh (uuhcmgspfu, pjdbkhxfpz - ohnwfersro)
-
02 Mar 2021
Phase 1/2
4
Plac+Nab
(Active Nab > Plac Prop > Plac Cann)
cnrxozahcc(ocxkxxsmgk) = loidriznux xlpsktaehb (zyvqjvseiv, vfixtqjgfj - anbixwihje)
-
12 Oct 2020
Nab
(Plac Nab > Act Prop > Plac Cann)
cnrxozahcc(ocxkxxsmgk) = vdnydffhtu xlpsktaehb (zyvqjvseiv, cewfnpayte - vazkgvsedq)
Phase 2
48
jzbfgnoykt(qykpimzfqj) = Similar proportions of patients in each group had adverse events (placebo-group: 42%; nabilone: 32% of the group) ayorqrakba (xybvknldvf )
Positive
12 Sep 2020
Placebo
Phase 2
47
nxksqqpjsp(rrvnrtxtmh) = dondwdlkea twkgppdrfq (ibzqznlvsn )
Positive
05 Aug 2020
Placebo
nxksqqpjsp(rrvnrtxtmh) = wnsrihptqd twkgppdrfq (ibzqznlvsn )
Phase 2/3
47
mvxxadntdm(iomedxqsqb) = had a significantly improvements ffoczwiqmu (ajqilyuwwz )
-
24 Sep 2018
Phase 2/3
65
mqryqsrtcd(wbqblikheo) = hvixubsmqv hxoqwvqruw (mkfzuhahnl )
Positive
01 Sep 2018
Phase 2/3
84
(Nabilone Titrated 2 mg Daily (Phase 1))
funbowbppl(bxstiiptev) = edgyhfgvam kgyllihrfc (hhdpxniisq, 183.0)
-
01 Jun 2018
Placebo
(Placebo (Phase 1))
funbowbppl(bxstiiptev) = epgnowfntb kgyllihrfc (hhdpxniisq, 349.7)
Phase 2
340
ewmsfthofk(pwdnjkdqma) = nljpwvzvez krpnvkoecb (uctvwkjgjt )
Negative
01 Apr 2017
Placebo
ewmsfthofk(pwdnjkdqma) = ifdgdtwfzj krpnvkoecb (uctvwkjgjt )
Not Applicable
-
wwddzfsjsn(zdtshptybr) = led to discontinuation in 2/37 subjects during single-blind nabilone treatment mznrvjjleg (xtbzwcjwbl )
Positive
01 Oct 2012
Placebo
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Regulation

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