Fluticasone Furoate/Umeclidinium Bromide/Vilanterol Trifenatate

BURLINGAME, Calif.--(BUSINESS WIRE)-- Innoviva, Inc. (NASDAQ: INVA) (“Innoviva” or the “Company”), a diversified holding company with a core royalties portfolio, a leading critical care and infectious disease platform known as Innoviva Specialty Therapeutics (“IST”), and a portfolio of strategic investments in healthcare assets, today announced that Pavel Raifeld, Chief Executive Officer, will present at the BofA Securities Health Care Conference in Las Vegas, NV on Wednesday, May 15, 2024 at 9:20 a.m. Pacific Daylight Time. A live webcast of the fireside chat can be accessed under “Events & Presentations” in the Investor Relations section of the Company’s website at . The webcast will be available for replay for 90 days following the event. About Innoviva Innoviva is a diversified holding company with a core royalties portfolio, a leading critical care and infectious disease platform known as Innoviva Specialty Therapeutics (IST), and a portfolio of strategic investments in healthcare assets. Innoviva’s royalty portfolio includes respiratory assets partnered with Glaxo Group Limited (GSK). Innoviva is entitled to receive royalties from GSK on sales of RELVAR®/BREO® ELLIPTA® and ANORO® ELLIPTA®. Innoviva’s other innovative healthcare assets include infectious disease and critical care assets stemming from acquisitions of Entasis Therapeutics, including XACDURO® (sulbactam for injection; durlobactam for injection), co-packaged for intravenous use approved for the treatment of adults with hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible strains of Acinetobacter baumannii-calcoaceticus complex and the investigational zoliflodacin currently being developed for the treatment of uncomplicated gonorrhea, and La Jolla Pharmaceutical Company, including GIAPREZA® (angiotensin II), approved to increase blood pressure in adults with septic or other distributive shock and XERAVA® (eravacycline) for the treatment of complicated intra-abdominal infections in adults. ANORO®, RELVAR®, BREO® and TRELEGY® are trademarks of the GSK group of companies. View source version on businesswire.com: Contacts Innoviva, Inc. David Patti Corporate Communications (908) 421-5971 david.patti@inva.com Investors and Media: Argot Partners (212) 600-1902 innoviva@argotpartners.com Source: Innoviva, Inc. View this news release online at:

Overall opioid utilization down nearly 10%; sustained-release opioids drop by over 10% SAN DIEGO, April 30, 2024 /PRNewswire/ -- Efforts by workers' comp regulators and professionals to control opioid prescriptions and distribution are resulting in one of the largest drops in utilization the workers' comp industry has seen in years, according to researchers who published part one of Enlyte's 2024 Annual Pharmacy Solutions Drug Trends Report today. Each year Enlyte researchers analyze drug utilization and spending trends in workers' comp to provide the industry with new insights in pharmacy management. Enlyte's 2024 series reflects on trends clients experienced in 2023, with an overview of both in- and out-of-network prescriptions. Among opioid categories, the report indicates decreases in utilization, including sustained-released opioids, which dropped by more than 10% in 2023, as supported by prescribing guidelines. Enlyte's data also shows overall opioid usage per claim dropped by nearly 10%, while cost per claim decreased by more than 7%. "This, by far, marks one of the largest drops in opioid utilization we've seen in years," said Nikki Wilson, PharmD, MBA, senior director, clinical pharmacy solutions. "In addition, opioid alternatives commonly prescribed to manage acute and chronic pain also experienced decreases in utilization per claim, although to a lesser degree than opioids." Researchers also noted per claim drops in overall drug cost and utilization in workers' comp among therapeutic classes ranked by cost in 2023. Though eight of the top 10 therapeutic classes experienced increased costs per script — with two classes rising by more than 10% — utilization per claim fell in every class except migraine medications, which jumped 17%. The largest script cost increases were within the respiratory and migraine medication classes at 14.7% and 10.2%, respectively, and both classes were among the top five therapeutic classes to experience brand average wholesale price increases in 2023, which likely contributed to the rising cost per script, said Wilson. "Basically, what's driving these trends are the costs of the top three medications in their respective classes," she said. "For instance, for migraine medications, Nurtec ODT is prescribed about 15% of the time yet makes up more than 31% of the total drug spend in this category. Similarly, respiratory medication like Trelegy Ellipta is prescribed about 10%, but accounts for nearly 19% of all respiratory medication total costs." Additionally, Enlyte data shows that retail and mail order prescriptions are trending downward with utilization per claim falling by more than 5% and cost per claim down by 0.2%. However, costs per script continue to rise, increasing from last year's report by 5.2%. To access part 1 of Enlyte's drug trends report, click here. About Enlyte Headquartered in San Diego, CA, Enlyte () is the parent company of Mitchell, Genex and Coventry, leaders in cost-containment technology, independent medical exams (IME), provider and specialty networks, case management services, pharmacy benefit and disability management. The Enlyte businesses align their joint industry expertise and advanced technology solutions in a combined organization of nearly 6,000 associates committed to simplifying and optimizing property, casualty and disability claims processes and services. SOURCE Enlyte