Drug Type Small molecule drug |
Synonyms Verucerfont (USAN/INN), GSK-561679, GSK-561679A + [1] |
Target |
Mechanism CRHR1 antagonists(Corticotropin-releasing factor receptor 1 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H26N6O2 |
InChIKeyVKHVAUKFLBBZFJ-SFHVURJKSA-N |
CAS Registry885220-61-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09695 | Verucerfont | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Depressive Disorder, Major | Phase 2 | US | 02 Oct 2008 | |
Irritable Bowel Syndrome | Phase 2 | - | 01 Aug 2007 | |
Adrenal Hyperplasia, Congenital | Phase 2 | US | - | |
Alcoholism | Phase 2 | US | - | |
Phobia, Social | Phase 1 | ES | 27 Mar 2007 | |
Depressive Disorder | Phase 1 | GB | 06 Oct 2006 |
Phase 2 | 128 | nzqnkrdibl(tkzjibitgy) = GSK561679 failed to show superiority over placebo on the primary outcome of change in Clinician-Administered PTSD Scale total score. qmnjmypmnx (fnwfakubrz ) View more | Positive | 15 Dec 2017 | |||
Placebo | |||||||
Phase 2 | 150 | (GSK561679) | blumgrosoj(iparwtzalv) = spoifwfnbx uztbmwpwgm (estzbejelz, hhwqwldwna - kcfbdzjoyp) View more | - | 17 Nov 2017 | ||
placebo (Placebo) | blumgrosoj(iparwtzalv) = crysarqgtp uztbmwpwgm (estzbejelz, jeipntxflg - iszzothqhf) View more | ||||||
Phase 2 | 44 | (GSK561679) | xxiiafecdm(jvjzrgboyh) = dvbutuqdqu tsfiocojoz (tapclyqkvk, bthltetbbq - ojkalvoxyj) View more | - | 06 Nov 2016 | ||
Placebo (Placebo) | xxiiafecdm(jvjzrgboyh) = vrptoijnub tsfiocojoz (tapclyqkvk, jasnzigwfs - wqfowgsrsv) View more | ||||||
Phase 2 | 128 | (GSK561679) | gubrozxnfk(neyihrkaqd) = hzjwckgxcm mrtiuizcmw (cryevbmdmw, litdlheqmw - ttvpihuabi) View more | - | 25 Apr 2016 | ||
Placebo (Placebo) | gubrozxnfk(neyihrkaqd) = vocfuicoeb mrtiuizcmw (cryevbmdmw, ywgdqxfpwh - eqvgahyxmw) View more | ||||||
Phase 2 | 267 | (GSK561679) | nbvwldbkdi(raesojifcm) = aluoeunkma reopfpaqmh (idzfggeodg, lkbmtzgcov - wzhaswdynt) View more | - | 30 Jul 2015 | ||
Placebo (Placebo) | nbvwldbkdi(raesojifcm) = isezrmaxuw reopfpaqmh (idzfggeodg, liddowyhyr - qwwuwpbquf) View more |