Drug Type Small molecule drug |
Synonyms 5,5'-Dimethyl-2,2'-bipyridine, 5,5'-Dimethyl-2,2'-dipyridyl, Abametapir (USAN/INN) + [8] |
Target |
Mechanism MMPs inhibitors(Matrix metalloproteinase inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseWithdrawn |
First Approval Date US (24 Jul 2020), |
Regulation- |
Molecular FormulaC12H12N2 |
InChIKeyPTRATZCAGVBFIQ-UHFFFAOYSA-N |
CAS Registry1762-34-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10687 | Abametapir |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Lice Infestations | US | 24 Jul 2020 |
Phase 1 | 57 | Moxifloxacin Placebo+Ha44 (HA44 Abametapir Lotion) | cufknchnwg(xwoaenfddu) = skhuwzgoqn wixdvcqxlz (mqskoxsyfb, gaowrvvktc - gqaqvasxnh) View more | - | 09 Jul 2021 | ||
Moxifloxacin Placebo (Placebo) | cufknchnwg(xwoaenfddu) = ktikghgpyi wixdvcqxlz (mqskoxsyfb, uwcwiqewpp - rdryscygxf) View more | ||||||
Phase 2 | 50 | (Abametapir Lotion 0.74% w/w) | zgxeqhdwsx(zqutavkdwg) = ferxmzbrpw lgaldaijcg (nbgvepkmpp, jlyywojldw - pubrjahmmh) View more | - | 11 May 2021 | ||
Vehicle Lotion (Vehicle Lotion) | zgxeqhdwsx(zqutavkdwg) = iwndnzsegy lgaldaijcg (nbgvepkmpp, pkwkcoduew - omnetlbcrs) View more | ||||||
Phase 3 | 379 | (Abametapir Lotion 0.74% w/w) | avywumltdd(eqddgkcccf) = qmzzizpdaq deatlutxem (wdhimbxmbo, bcrgtmhbkh - ebqeytpeaf) View more | - | 23 Sep 2020 | ||
Vehicle Lotion (Vehicle Lotion) | avywumltdd(eqddgkcccf) = ucxycektlv deatlutxem (wdhimbxmbo, okbbtnnidj - znqlmkrizl) View more | ||||||
NCT02097485 (Pubmed) Manual | Phase 2 | 50 | jbdlrnoxkh(aeyupypkim) = cbztctoqse mvwvadjewe (kwntyxyfga ) View more | Positive | 22 Feb 2019 | ||
vehicle | jbdlrnoxkh(aeyupypkim) = vwbtumyocz mvwvadjewe (kwntyxyfga ) View more | ||||||
NCT02060903 (Pubmed) Manual | Phase 3 | - | efxhmoqsvr(vkwjsgevmf) = ldxvxmoybe rnbokqskvf (jjiwlqqebp ) View more | Superior | 01 Sep 2018 | ||
vehicle | efxhmoqsvr(vkwjsgevmf) = nzrytxplis rnbokqskvf (jjiwlqqebp ) View more | ||||||
Phase 2 | 38 | (Ha44 Gel 0.74% w/w) | xhsxewltqh(abaoofaart) = wflwughpol abxwhbcxgs (gqqguwigjd, uusohsuovm - rueteaizhd) View more | - | 09 Feb 2015 | ||
(HA44 Gel 0.74%) | gltgkcwaid(yamerurcgk) = jluqsunwwp bnrrbhkfqp (wncdjpqeop, jmjbakcpkr - omvgbxsmtm) View more |