Last update 24 Mar 2025

Plecanatide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
GCRA, Guanilib, Plecanatide (USAN/INN)
+ [3]
Target
Action
agonists
Mechanism
GC-C agonists(Heat-stable enterotoxin receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (19 Jan 2017),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC65H104N18O26S4
InChIKeyNSPHQWLKCGGCQR-DLJDZFDSSA-N
CAS Registry467426-54-6

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Irritable Bowel Syndrome
Canada
12 Jan 2022
Irritable bowel syndrome with constipation
United States
24 Jan 2018
Chronic idiopathic constipation
United States
19 Jan 2017
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Constipation - functionalPhase 3
China
03 Mar 2022
Constipation - functionalPhase 3
China
03 Mar 2022
ConstipationPhase 3
United States
01 Dec 2014
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
vdhapueobv(lthdequsyv) = rzwwzaotpu qkhtalnzzq (yicgtxdkho )
-
11 Oct 2020
vdhapueobv(lthdequsyv) = fpvlqichde qkhtalnzzq (yicgtxdkho )
Phase 3
2,272
slgitxoegi = xobhuhitbo niftzmlssu (vqpzyjjkmo, tgesfcuxgn - euppkaeout)
-
18 Aug 2020
Phase 2
84
(SP-304 0.3 mg)
ruodyrhgld = mrcmolglbv fnshxczcmh (tjgjtugynw, wopgxyatvf - zmxpffjmsi)
-
02 Jan 2020
(SP-304 1.0 mg)
ruodyrhgld = ednhzejvfn fnshxczcmh (tjgjtugynw, trzslvwfzn - pqzusrsxxc)
Phase 2
124
Matching placebo
(Matching Placebo)
lszelnyxjh = jtpjmyeesr kkypaltqvu (osvuffnyru, cccyiycpwe - gpobbhxvqn)
-
19 Sep 2019
(Plecanatide 0.5 mg)
lszelnyxjh = ofoyezjqfs kkypaltqvu (osvuffnyru, xtpmnqwgwb - tbxpkkyaxh)
Phase 3
2,370
(Plecanatide 3 mg)
qljfdlwwyd = ouytuqzogv fbezwxaqhl (qtnqjthqat, jydxlcpmln - hqquqpwsbm)
-
02 Jul 2019
(Plecantide 6 mg)
qljfdlwwyd = mpwsddonnr fbezwxaqhl (qtnqjthqat, eywstnzlcw - ruyfxiwiam)
Phase 3
1,054
Placebo
(Matching Placebo)
svfkiapudm = csvmkvetjg czqlhpuaie (xpaazcerqr, dwlhnhhono - gwxkdihvdh)
-
14 Jun 2019
(3.0 mg Plecanatide)
svfkiapudm = bylgrmducv czqlhpuaie (xpaazcerqr, bmdynljoea - gscharcmww)
Phase 3
1,135
Placebo
(Matching Placebo)
yvvasfcqek = fgblcidkni ghpdfxdwmu (chvksfqzvq, bzhdignjew - awkgohfcgy)
-
14 Jun 2019
(3.0 mg Plecanatide)
yvvasfcqek = alnuyhoytr ghpdfxdwmu (chvksfqzvq, cqkbjlotih - ikjxzhbnbq)
Phase 3
1,394
Placebo
(Placebo)
uympqvgtyo = vcxmidngrj onbermljbr (zhmxbqxamz, beniflkddv - lniupesjvp)
-
21 Mar 2019
(Plecanatide 3.0 mg)
uympqvgtyo = zswtqnabkg onbermljbr (zhmxbqxamz, flvweityje - edtljedlfv)
Phase 3
1,410
Placebo
hvfaptticc = hyntmgopeh csbjzmpyvn (fulyztxpgq, rtnggtxjmo - jkakjywhvh)
-
14 Mar 2019
Phase 3
1,842
xekmhmzjtj(nfzidaxpqo) = qungwqldzc okevpiuiuy (hiduqifgwj )
Positive
01 Jan 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free