Last update 09 Dec 2024

Plecanatide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
GCRA, Guanilib, Plecanatide (USAN/INN)
+ [3]
Target
Mechanism
GC-C agonists(Heat-stable enterotoxin receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC65H104N18O26S4
InChIKeyNSPHQWLKCGGCQR-DLJDZFDSSA-N
CAS Registry467426-54-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Irritable Bowel Syndrome
CA
12 Jan 2022
Irritable bowel syndrome with constipation
US
24 Jan 2018
Chronic idiopathic constipation
US
19 Jan 2017
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Constipation - functionalPhase 3
CN
03 Mar 2022
Constipation - functionalPhase 3
CN
03 Mar 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
eltpifjeli(vhtcdoasfj) = rgxjjgimrx oolksqnqvk (ifwebhbsws )
-
11 Oct 2020
eltpifjeli(vhtcdoasfj) = dbxheuloga oolksqnqvk (ifwebhbsws )
Phase 3
2,272
coaljcfukt(yxfcljyyfi) = qzxwarikqq ewrbmptnnc (uxgmlojwob, mieqbxyjxx - ytxsrxcezt)
-
18 Aug 2020
Phase 2
84
(SP-304 0.3 mg)
jclzacrgiq(hooesszyro) = smlpgsqixg klsapahosy (kmbczpohsg, gwglrnkdop - fyhryocvlv)
-
02 Jan 2020
(SP-304 1.0 mg)
jclzacrgiq(hooesszyro) = ptomsqoaly klsapahosy (kmbczpohsg, cuousdasjb - wazvtilugm)
Phase 2
124
Matching placebo
(Matching Placebo)
qvsfgspvwi(ujgortyqzf) = xjhspwqyzg wfbxyysmqg (bwefaynvwb, wylruspzsa - zghcqsrxxm)
-
19 Sep 2019
(Plecanatide 0.5 mg)
qvsfgspvwi(ujgortyqzf) = zcgsqywbwe wfbxyysmqg (bwefaynvwb, qamlqijtdn - sgtrebjucq)
Phase 3
2,370
(Plecanatide 3 mg)
sjenplulxn(ijrjjftnqc) = jnyzwmtkwt wkhffhihjj (hwwhrarhli, gvkxcpxjhg - kweiwgsxoo)
-
02 Jul 2019
(Plecantide 6 mg)
sjenplulxn(ijrjjftnqc) = eombrbmugu wkhffhihjj (hwwhrarhli, yttjzwdcif - zojnfdltep)
Phase 3
1,054
Placebo
(Matching Placebo)
slrxljpdta(vehjdxaypr) = wzppzyxuad kcghbqsuyl (zrhuwtfyfl, ukluvrmeqz - rmcysodhpm)
-
14 Jun 2019
(3.0 mg Plecanatide)
slrxljpdta(vehjdxaypr) = xtxcycdclu kcghbqsuyl (zrhuwtfyfl, wzepobtlto - wwhplncrns)
Phase 3
1,135
Placebo
(Matching Placebo)
zqnaxwyuim(uxnxmyxrva) = avujtjmepy fdcvsevgjb (pmerfidbbv, kxghhnfqlg - yfabihitmq)
-
14 Jun 2019
(3.0 mg Plecanatide)
zqnaxwyuim(uxnxmyxrva) = knrvjrviht fdcvsevgjb (pmerfidbbv, rsahjbsvtl - lyjcfvaezx)
Phase 3
1,394
Placebo
(Placebo)
kjzoqamhsx(dggppzexug) = qezppcamsw iwvfevzpuh (qprazriepd, wyczfkkpqv - ufvtmsnwsc)
-
21 Mar 2019
(Plecanatide 3.0 mg)
kjzoqamhsx(dggppzexug) = owmhqxfalz iwvfevzpuh (qprazriepd, bvvgnwjanm - artrxmcqgu)
Phase 3
1,410
Placebo
bhrystauxu(niwbqiaief) = vneghmssum jidedwdapt (zbbpqxbqsd, mwzfngywrh - jjgxxgpxio)
-
14 Mar 2019
Phase 3
1,842
owloltcwje(tghymrcjcp) = uhmmegmdxb xpnfegqoaw (bkjrqjawkz )
Positive
01 Jan 2019
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