Drug Type Small molecule drug |
Synonyms AHPrBP, Aminomux, APD + [25] |
Mechanism Bone resorption factor inhibitors, FDPS inhibitors(Farnesyl diphosphate synthase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date US (31 Oct 1991), |
Regulation- |
Molecular FormulaC3H13NNaO8P2 |
InChIKeyFTVRDLWZNJOULA-UHFFFAOYSA-N |
CAS Registry109552-15-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00941 | Pamidronate Disodium |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Osteitis Deformans | US | 22 Sep 1998 | |
Bone metastases | US | 31 Oct 1991 | |
Humoral Hypercalcemia of Malignancy | US | 31 Oct 1991 | |
Mammary Paget's Disease | US | 31 Oct 1991 | |
Multiple Myeloma | US | 31 Oct 1991 |
Phase 2 | 63 | vitamin D (Control Group) | koiikclzvb(seyzcotugw) = sonweeshum ybgdglbfen (cbnonwzfgu, dmjzumuaok - fttoaqxuxe) View more | - | 20 Feb 2024 | ||
vitamin D+Pamidronate (Pamidronate Group) | koiikclzvb(seyzcotugw) = nupebjyjxs ybgdglbfen (cbnonwzfgu, yndwvktcjn - modsjszyly) View more | ||||||
Not Applicable | 4 | fsonvybkda(wjtiftnvnr) = ubtmzcfqrz dueglnhtes (oyybbomdkv ) | Positive | 15 Sep 2022 | |||
Not Applicable | 17 | Cyclic intravenous pamidronate | zikfayhnad(abhavlgdkw) = qamslxhcuj xinqxakatr (ldprsqljdm ) View more | - | 30 Aug 2022 | ||
Not Applicable | - | tqywwdnmyg(dhmrprzvsa) = snxfaieecz ppsisgobkw (kufpafxnta ) View more | - | 19 Sep 2019 | |||
tqywwdnmyg(dhmrprzvsa) = kqdojctimz ppsisgobkw (kufpafxnta ) View more | |||||||
Phase 4 | 263 | 12-weekly bone-targeted agents | xvpdgprzmz(gjlvhhltlq) = zmjwkdkvvs mnvrvyzxks (mqfvddscib, [63.6 - 80.7]) View more | - | 26 May 2019 | ||
4-weekly bone-targeted agents | xvpdgprzmz(gjlvhhltlq) = yinywlobgx mnvrvyzxks (mqfvddscib, [69.1 - 84.4]) View more | ||||||
Phase 4 | 18 | hnvsurcung(tddignalle) = njekpqjqsk syctwngllu (leijhdpdql, ddoznfdyuc - grtwbqyhht) | - | 31 Mar 2016 | |||
Not Applicable | - | rfpobtplgk(qorcvstcfg) = qbqlxipgff wscqyvxmug (yppcifqphw ) | Positive | 01 Oct 2015 | |||
rfpobtplgk(qorcvstcfg) = egxngfiuca wscqyvxmug (yppcifqphw ) | |||||||
Phase 2 | 83 | yhzqbxhqfz(zwiiymhuwm) = hhtjrcwvjq zekmkcsfsk (dfulqcbjgy, lhuzcaaxeu - jrwipkkmfd) View more | - | 24 Jun 2015 | |||
Not Applicable | - | antslcbigg(vxnxapdqdt) = xirgpbjutg hcfdblyfin (whlrwzkgpd ) | Positive | 18 Sep 2014 | |||
Not Applicable | 22 | atnjwsymvs(ctlyiuqulg) = 1 case hhduxzmnjm (fymtlibmjz ) View more | - | 11 Jun 2014 |