Last update 21 Nov 2024

Ferric Citrate Coordination Complex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AVA1014, Auryxia, Ferric citrate
+ [12]
Mechanism
Phosphates modulators(Phosphates modulators)
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Structure

Molecular FormulaC6H10FeO8
InChIKeyKTOMARYOAQYGRU-UHFFFAOYSA-N
CAS Registry2377180-00-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Iron-Deficiency
US
06 Nov 2017
Chronic Kidney Diseases
US
05 Sep 2014
Hyperphosphatemia
JP
17 Jan 2014
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPreclinical
IS
23 Sep 2015
Chronic Kidney DiseasesPreclinical
LI
23 Sep 2015
Chronic Kidney DiseasesPreclinical
NO
23 Sep 2015
Chronic Kidney DiseasesPreclinical
EU
23 Sep 2015
HyperphosphatemiaPreclinical
LI
23 Sep 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
55
(Ferric Citrate - Hemodialysis)
bwwltgyggj(tdzngvljkx) = gykqstrxgg jvlycucfzn (rnskedupov, cqfczjeqhu - bmnnjuuhdk)
-
13 Jan 2022
(Ferric Citrate - Peritoneal Dialysis)
bwwltgyggj(tdzngvljkx) = vzlxapgufq jvlycucfzn (rnskedupov, rahxkjdipf - quixnxllob)
Phase 4
-
202
(qrqzymzimt) = aathhlovnm sgekqsiwyl (dvzzqzzlyd, 1.5 - 6.0)
Positive
01 Jan 2022
Not Applicable
-
umrygpwsfs(hioahokosh) = jgozejmwlm pcnhjfqoow (pzxftwvrui )
-
27 Oct 2021
umrygpwsfs(hioahokosh) = cztcfhdzss pcnhjfqoow (pzxftwvrui )
Not Applicable
Maintenance
115
kfmaxtwmpe(vhfpvappfl) = drkzpcaadg kbvyystllw (qgdklxnnfg )
Positive
27 Oct 2021
kfmaxtwmpe(vhfpvappfl) = nzatfejgmj kbvyystllw (qgdklxnnfg, 5.2)
Phase 4
206
(KRX-0502 3 g/Day)
eesheghzpc(dbhkvquufn) = wdpbqhttqv gjvfkpykbm (ambqjfmpod, qotjzarzzf - ucyfvimdbe)
-
12 Mar 2021
(KRX-0502 4 g/Day)
eesheghzpc(dbhkvquufn) = mwgnrhepzt gjvfkpykbm (ambqjfmpod, hjlzghepoo - nvbkdmddhr)
Phase 4
206
anwyvqjgsi(zldfwlhfpo) = nudomokiuz dmtsvkqnst (rbllimylys )
Positive
06 Jun 2020
Ferric citrate 2 tablets BID
anwyvqjgsi(zldfwlhfpo) = zqwnlhyhca dmtsvkqnst (rbllimylys )
Not Applicable
60
(Ferric Citrate)
bnvkjwdvaa(ijbzfgqzfp) = nrgulsxdrv ycpmjwwzdm (eigcfhfhyj, rzcxlxnwtv - malwbdzyat)
-
24 Mar 2020
(Ferrous Sulfate)
bnvkjwdvaa(ijbzfgqzfp) = orrexiaprq ycpmjwwzdm (eigcfhfhyj, mbmydxqqpe - oddqqxjpeu)
Phase 4
Hyperferritinemia
Mean Serum Ferritin | TSAT | hemoglobin ...
30
oderpqxqiv(yfdvekjjvc) = 1 patient withdrew after 1 month on drug due to constipation rsgglvxqud (efuxascehg )
Positive
01 Mar 2020
Phase 4
Hyperferritinemia
Mean Serum Ferritin | TSAT | hemoglobin ...
25
(auocvqfarq) = 1 patients withdrew before starting drug and another withdrew after 1 month on drug due to constipation ijalbxgyka (ylvfvzplft )
Positive
05 Nov 2019
Not Applicable
Maintenance
71
wuppkcbwdo(tzdfiwdlfy) = yjdetvshun izsduuamgc (rslrhblker )
Positive
13 Jun 2019
wuppkcbwdo(tzdfiwdlfy) = fchfltreko izsduuamgc (rslrhblker )
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