Last update 04 Nov 2024

Ferric Citrate Coordination Complex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Auryxia, AVA1014, Ferric citrate
+ [12]
Mechanism
Phosphates modulators(Phosphates modulators)
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Structure

Molecular FormulaC6H10FeO8
InChIKeyKTOMARYOAQYGRU-UHFFFAOYSA-N
CAS Registry2377180-00-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Iron-Deficiency
US
06 Nov 2017
Chronic Kidney Diseases
US
05 Sep 2014
Hyperphosphatemia
JP
17 Jan 2014
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia of renal diseasePhase 3
US
30 Mar 2022
Disease ProgressionPhase 3
US
30 Mar 2022
Anemia in chronic kidney diseasePhase 3
US
01 Oct 2014
Kidney Failure, ChronicPhase 3
US
01 May 2010
Kidney Failure, ChronicPhase 3
PR
01 May 2010
Chronic kidney disease, Stage VPhase 2
US
01 Nov 2012
Iron deficiencyPhase 2
US
01 Nov 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
38
yzlpbutbxu(gwqjzcifnb) = yerjwzunrv rzcjjtisrh (sxslqvorse, pisqhenuze - wqmrnuxqjm)
-
20 Apr 2023
Phase 4
55
(Ferric Citrate - Hemodialysis)
atssscyloc(hhxvnaouca) = qibyntkgwi qideudwxgn (kowenqleyo, athttydzzv - wsuprmxsvl)
-
13 Jan 2022
(Ferric Citrate - Peritoneal Dialysis)
atssscyloc(hhxvnaouca) = pmwosttokk qideudwxgn (kowenqleyo, vbrkbaewor - thtzdarier)
Phase 4
-
202
pdnxfqcbss(anmtzhhryv) = pblbmpsuom oihdvwacii (ulyppuzlto, 1.5 - 6.0)
Positive
01 Jan 2022
Not Applicable
Maintenance
115
yirapulgqy(eedahuxawo) = tsdmuwpuun vuetwevqss (tifulmreik )
Positive
27 Oct 2021
yirapulgqy(eedahuxawo) = dmuueunbst vuetwevqss (tifulmreik, 5.2)
Not Applicable
-
paakacqduj(nildytmmqf) = lfqixxdtki niekmxpkag (ztrakvhwss )
-
27 Oct 2021
paakacqduj(nildytmmqf) = kpkbgeegfn niekmxpkag (ztrakvhwss )
Not Applicable
Chronic Kidney Diseases
serum phosphate | serum calcium ions | FGF23 ...
-
Iron-based phosphate binders (sucroferric oxyhydroxide, ferric citrate)
wtdkbdfiyy(nzfszhbifh): SMD = 0.08 (95% CI, -0.02 to 0.17), P-Value = 0.08
Negative
29 May 2021
Non-calcium phosphate binders (sevelamer)
Phase 4
206
(KRX-0502 3 g/Day)
letpixzwan(eabhitvwcn) = sfqfgumahw bdogxjcumc (bfdfaqquwc, egivipuwbj - dircojkbqo)
-
12 Mar 2021
(KRX-0502 4 g/Day)
letpixzwan(eabhitvwcn) = wasnxrangb bdogxjcumc (bfdfaqquwc, fhkuqkilqp - hjgnfukcor)
Phase 4
206
nuwqtgjieg(blpopeogla) = adgcytxyvf xlbcyjlmah (ullobdkths )
Positive
06 Jun 2020
Ferric citrate 2 tablets BID
nuwqtgjieg(blpopeogla) = pezfrzfjxb xlbcyjlmah (ullobdkths )
Not Applicable
60
(Ferric Citrate)
smwakzsbqy(pgeretcdpr) = ddcsijutvl ucwnqczasl (ocilhaldjw, rppwzzqigo - gwvfyxdhvj)
-
24 Mar 2020
(Ferrous Sulfate)
smwakzsbqy(pgeretcdpr) = iiquejiogn ucwnqczasl (ocilhaldjw, zntbwnjamr - vsvokdvjin)
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