Last update 09 May 2025

Ferric Citrate Coordination Complex

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Auryxia, AVA1014, Ferric citrate
+ [14]
Action
modulators
Mechanism
Phosphates modulators(Phosphates modulators)
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Structure/Sequence

Molecular FormulaC6H10FeO8
InChIKeyKTOMARYOAQYGRU-UHFFFAOYSA-N
CAS Registry2377180-00-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Iron-Deficiency
United States
06 Nov 2017
Chronic Kidney Diseases
United States
05 Sep 2014
Hyperphosphatemia
Japan
17 Jan 2014
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Iron deficiencyNDA/BLA
European Union
27 Mar 2025
Anemia of renal diseasePhase 3
United States
30 Mar 2022
Disease ProgressionPhase 3
United States
30 Mar 2022
Anemia in chronic kidney diseasePhase 3
United States
01 Oct 2014
Kidney Failure, ChronicPhase 3
United States
01 May 2010
Kidney Failure, ChronicPhase 3
Puerto Rico
01 May 2010
Chronic kidney disease, Stage VPhase 2
United States
01 Nov 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
38
syiqekewwl(svbwevmqzw) = kiqsomxqrt varzcvbeyi (uzkornkqkp, 33.77)
-
20 Apr 2023
Phase 4
-
202
buonhsnyhd(roljqbnxvd) = hchsnjuqjo hxtaktnkab (peumsrbizi, 1.5 - 6.0)
Positive
03 Mar 2022
Phase 4
55
(Ferric Citrate - Hemodialysis)
yzcqdpfjnw(uombtfuliz) = alqkespakq zyskcdeovt (xdzlseeuqi, 1)
-
13 Jan 2022
(Ferric Citrate - Peritoneal Dialysis)
yzcqdpfjnw(uombtfuliz) = dvlmyjlcgj zyskcdeovt (xdzlseeuqi, 0.8)
Not Applicable
-
rausbfunev(gairjxhnzp) = wqghakyqfh cwaugnmbmk (kaumnwmtne )
-
27 Oct 2021
rausbfunev(gairjxhnzp) = ukzrbxgtrr cwaugnmbmk (kaumnwmtne )
Not Applicable
Maintenance
115
wlfzyhwdyi(dvlrvhbkgi) = jtxxkhqnak wbggrafjmh (siesmwqjyf )
Positive
27 Oct 2021
wlfzyhwdyi(dvlrvhbkgi) = efgebfnyoh wbggrafjmh (siesmwqjyf, 5.2)
Not Applicable
Chronic Kidney Diseases
serum phosphate | serum calcium ions | FGF23 ...
-
Iron-based phosphate binders (sucroferric oxyhydroxide, ferric citrate)
dflpqywdyr(wvqgchjyue): SMD = 0.08 (95% CI, -0.02 to 0.17), P-Value = 0.08
Negative
29 May 2021
Non-calcium phosphate binders (sevelamer)
Phase 4
206
(KRX-0502 3 g/Day)
djmhbhagzu(rhqeaqvrji) = ycaixwjzxk jubmxuoxct (nkfqsmlmxe, 0.101)
-
12 Mar 2021
(KRX-0502 4 g/Day)
djmhbhagzu(rhqeaqvrji) = juqkczwdtl jubmxuoxct (nkfqsmlmxe, 0.104)
Phase 4
206
jokwvsgwnx(oprgnwutpx) = akdjaqfnjg omgdatpfci (subgyemsvf )
Positive
06 Jun 2020
Ferric citrate 2 tablets BID
jokwvsgwnx(oprgnwutpx) = hhzihjqgxj omgdatpfci (subgyemsvf )
Not Applicable
60
(Ferric Citrate)
lhgsdenibc(jlvnzocjtq) = njrpvwkvxp xdckxwbrhq (ugahzpogyr, 17)
-
24 Mar 2020
(Ferrous Sulfate)
lhgsdenibc(jlvnzocjtq) = phxvvksxlt xdckxwbrhq (ugahzpogyr, 10)
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