Drug Type Small molecule drug |
Synonyms N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Tranilast (JP17/USAN/INN) + [9] |
Target |
Action inhibitors |
Mechanism TGF-β inhibitors(Transforming growth factor beta inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (15 Jun 1982), |
RegulationOrphan Drug (European Union) |
Molecular FormulaC18H17NO5 |
InChIKeyNZHGWWWHIYHZNX-UHFFFAOYSA-N |
CAS Registry53902-12-8 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Asthma | China | 28 Feb 2011 | |
Dermatitis, Atopic | China | 28 Feb 2011 | |
Conjunctivitis, Allergic | Japan | 29 Sep 1995 | |
Conjunctivitis, Allergic | Japan | 29 Sep 1995 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pterygium | Phase 3 | Brazil | 01 Jan 2015 | |
Rheumatoid Arthritis | Discovery | United Kingdom | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | Argentina | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | United States | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | Serbia | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | Mexico | 01 Mar 2009 |
Not Applicable | - | - | (Irradiation Group) | (cdbmvncsob) = eauonmjhsd cqcutlhdcj (vbuyeugved ) View more | - | 15 Oct 2023 | |
Tranilast Pre-treated Irradiation Group | (cdbmvncsob) = ypvdufpdtj cqcutlhdcj (vbuyeugved ) View more | ||||||
Not Applicable | Dermatomyositis TIF-g | NXP-2 | 111 | (Antibodies to TIF-g) | monwtcioqc(wyhgxukswl) = zearzkhhpn wwyfdtuybn (rkzzzraveq ) | - | 09 Nov 2012 | |
Not Applicable | - | unvrphqkdd(icgnqotxax) = faljzzdccl vrsohqjzbh (wiziqxrfak ) | - | 01 Nov 2006 | |||
Vehicle | unvrphqkdd(icgnqotxax) = pjzsbgloga vrsohqjzbh (wiziqxrfak ) | ||||||
Not Applicable | - | 4 | osusawohex(tvxglahsit) = vlddowabrc utfwhmsjjp (gkzpgegczl ) | Positive | 01 May 2006 | ||
Phase 3 | - | 32 | gvppmdaxsu(cbrkrqypsx) = bkqjtgywjn dswclwbwfd (krhdvvwnjr ) View more | - | 01 Mar 2004 |