Drug Type Small molecule drug |
Synonyms fostrox, Fostroxacitabine Bralpamide Hydrochloride, MIV 818 + [2] |
Target |
Mechanism DNA inhibitors(DNA inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H30BrN4O8P |
InChIKeyJBYKMODFCUCTGY-LLSQRQBFSA-N |
CAS Registry2129993-56-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hepatocellular Carcinoma | Phase 2 | BE | 05 Sep 2018 | |
Hepatocellular Carcinoma | Phase 2 | KR | 05 Sep 2018 | |
Hepatocellular Carcinoma | Phase 2 | ES | 05 Sep 2018 | |
Hepatocellular Carcinoma | Phase 2 | GB | 05 Sep 2018 | |
Intrahepatic Cholangiocarcinoma | Phase 2 | BE | 05 Sep 2018 | |
Intrahepatic Cholangiocarcinoma | Phase 2 | KR | 05 Sep 2018 | |
Intrahepatic Cholangiocarcinoma | Phase 2 | ES | 05 Sep 2018 | |
Intrahepatic Cholangiocarcinoma | Phase 2 | GB | 05 Sep 2018 | |
Liver metastases | Phase 2 | BE | 05 Sep 2018 | |
Liver metastases | Phase 2 | KR | 05 Sep 2018 |
Phase 1/2 | 18 | eqtqhkurvk(sdnuihcepe) = daglelacep mvlvqskgyr (euuwfghqaa ) View more | Positive | 18 Jan 2024 | |||
PRNewswire Manual | Phase 1/2 | - | nmuvhulzie(svmdchfjag) = xyiwzrcfgo avgwlckrxj (ghvdrrlvxw ) View more | Positive | 19 Dec 2023 | ||
Phase 2 | 20 | aanfiapwjd(cwoicgswnv) = The combination remains tolerable with no unexpected new safety events and adverse events are transient and manageable. diilwmcmkm (rwghnpiuxs ) | Positive | 05 Oct 2023 | |||
Phase 1/2 | 6 | jmoekolylu(ewzsrwuzgn) = raxqfslvkh nofqixrzto (hfzhgficgn ) View more | Positive | 04 Sep 2023 | |||
Not Applicable | - | tzfqimyvip(zqriwiwzlb) = wclqxvlesp zlxxgexppw (htvqhjhwmt ) | - | 03 Feb 2022 | |||
Phase 1 | 9 | pkgrncdxox(njxklgcfmc) = The most common treatment emergent AEs were those in the haematological system; raised LFTs and pruritus were also commonly reported. dccavdohql (kievgqccqx ) View more | Positive | 16 Sep 2021 |