Last update 26 Jun 2025

ALG-055009

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ALG 055009, ALG055009
Target
Action
agonists
Mechanism
THR-β agonists(Thyroid hormone receptor beta agonists)
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC16H14Cl2N6O4
InChIKeyYZZBNKVFMULQCU-UHFFFAOYSA-N
CAS Registry2542029-03-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nonalcoholic SteatohepatitisPhase 2
United States
01 Apr 2024
HyperlipidemiasPhase 1
France
01 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
18
ALG-055009 Doses of 0.5 mg to 0.9 mg
yffryfhvsi(vkokozotnu) = mzfsfjubtc sxmsgkousz (skxvvwvtwl )
Met
Positive
26 Mar 2025
Placebo
-
Phase 2
102
ALG 055009 0.3 mg
eodtuiekim(mlgdpdeylq) = pipugsrbkw uhousqvcde (fjqhnhdeaj )
Met
Positive
19 Sep 2024
ALG 055009 0.5 mg
eodtuiekim(mlgdpdeylq) = ubugktsaaj uhousqvcde (fjqhnhdeaj )
Met
Phase 1
-
sbyqhadgre(mnazhpwehl) = Expected thyromimetic effects were observed: dose-dependent increases in sex hormone binding globulin levels (SHBG) and decreases in lipid levels csgochyftp (tbeaklplnf )
Positive
07 Dec 2023
Phase 1
-
icmttrncue(vdrbohlzbe) = well tolerated with no safety signals identified niiwrnuqrn (xqvruxdtha )
Positive
13 Nov 2023
Phase 1
40
nvhwljebdc(albtwitmxl) = There were no serious adverse events, dose-limiting toxicities, or TEAEs leading to premature discontinuation ggvrnmanfv (tefqzyhrio )
Positive
04 Nov 2022
Placebo
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Core Patent

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Clinical Trial

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Approval

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Regulation

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