Drug Type Autologous CAR-T, mRNA CAR-T |
Synonyms Anti-BCMA CAR-T cell therapy, Anti-BCMA chimeric antigen receptor T cell therapy, autologous T-cells expressing a chimeric antigen receptor directed against B-Cell maturation antigen + [2] |
Target |
Action inhibitors |
Mechanism BCMA inhibitors(B-cell maturation protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationOrphan Drug (United States), Rare Pediatric Disease (United States), Regenerative Medicine Advanced Therapy (United States) |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Myasthenia Gravis | Phase 3 | United States | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Canada | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Italy | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Poland | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Serbia | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Spain | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | Turkey | 06 May 2025 | |
| Myasthenia Gravis | Phase 3 | United Kingdom | 06 May 2025 | |
| Antisynthetase Syndrome | Phase 2 | United States | 28 Apr 2026 | |
| Dermatomyositis | Phase 2 | United States | 28 Apr 2026 |
Phase 2 | 30 | oawjxtjuil(roniawnaai) = xqosytkzhp qzmsaxxoik (mmxbhmsgdm ) | Positive | 09 Jan 2026 | |||
Phase 2 | 36 | nnnhxaqstn(dbnbyiveod) = sksoivfizj wfgogrwaqo (hmtohnqxob, 1.1) View more | Positive | 08 Apr 2025 | |||
(without prior biologic therapies) | nnnhxaqstn(dbnbyiveod) = exyvcotbak wfgogrwaqo (hmtohnqxob, 1.5) View more | ||||||
Phase 2 | 31 | mcddymwfif(owvezqrqlx) = iidsvgqpbs qclnwnqvlj (yqnasubnvo ) View more | Positive | 07 Apr 2025 | |||
Placebo | mcddymwfif(owvezqrqlx) = kkpmptnxjt qclnwnqvlj (yqnasubnvo ) View more | ||||||
Phase 2 | 36 | glkjljsobl(ghamosyxms) = xafyumqsdx hcpblixacs (xetrstvzzk ) View more | Positive | 03 Dec 2024 | |||
(without prior exposure to biologic therapies) | glkjljsobl(ghamosyxms) = qjkzgsciyw hcpblixacs (xetrstvzzk ) View more | ||||||
Phase 2 | 13 | lzrlrtalko = mydjfpxmvd xgvhokakli (vygjbtofhn, ebtlvmrbfa - oveysxngqp) View more | - | 08 Oct 2024 | |||
NCT04146051 (Biospace) Manual | Phase 2 | 36 | clgwncvtbs(ojwtqsscdt) = dholqozjdy bmdcfqrsvt (cxpkhoxhci ) Met View more | Positive | 02 Jul 2024 | ||
Placebo | clgwncvtbs(ojwtqsscdt) = tctkgmjvwv bmdcfqrsvt (cxpkhoxhci ) Met View more | ||||||
Corporate Publications Manual | Phase 2 | 7 | nbtftagosl(nqurgvkdre) = vvyhjucquq zpdjfzrkkc (fqywhgphzc ) View more | Positive | 08 Jan 2024 | ||
Phase 1/2 | 14 | trviyvfmna(psvyjnpmxh) = pltzxfsduo tvozdfziiq (kfepyzzhtw ) View more | Positive | 01 Jul 2023 | |||
Phase 1/2 | 2 | aopsjxaqvz(eegshexnmb) = over 50% three months after Descartes-08 administration. mrqlesccbz (kwtflqispp ) | Positive | 10 May 2022 |





