Drug Type Small molecule drug |
Synonyms Doripenem Hydrate, Doripenem hydrate (JP17), doripenem monohydrate + [9] |
Target |
Action inhibitors |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (25 Jul 2005), |
RegulationOrphan Drug (United States) |
Molecular FormulaC15H26N4O7S2 |
InChIKeyNTUBEBXBDGKBTJ-WGLOMNHJSA-N |
CAS Registry364622-82-2 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Meningococcal Infections | Japan | 17 Mar 2015 | |
| Paediatric infections | Japan | 10 Apr 2013 | |
| Hospital-acquired pneumonia | European Union | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Iceland | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Liechtenstein | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Norway | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | European Union | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Iceland | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Liechtenstein | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Norway | 25 Jul 2008 | |
| Complicated intra-abdominal infection | United States | 12 Oct 2007 | |
| Complicated urinary tract infection | United States | 12 Oct 2007 | |
| Pyelonephritis | United States | 12 Oct 2007 | |
| Gram-Negative Bacterial Infections | Japan | 08 Sep 2005 | |
| Gram-Positive Bacterial Infections | Japan | 03 Sep 2005 | |
| Urinary Tract Infections | Japan | 30 Aug 2005 | |
| Bacterial Infections | Japan | 25 Jul 2005 | |
| Respiratory Tract Infections | Japan | 25 Jul 2005 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Abdomen, Acute | Phase 3 | United States | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Argentina | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Brazil | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Chile | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Colombia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Latvia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Lithuania | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Panama | 01 Dec 2010 | |
| Abdominal Abscess | Phase 3 | United States | 01 Dec 2010 | |
| Abdominal Abscess | Phase 3 | Argentina | 01 Dec 2010 |
Phase 3 | - | 13 | Doripenem 1 g q8h | kpimdjdesv(vjseizoadu) = znlbnmvaln varozobwbz (pjxlsuiayc ) View more | - | 28 Dec 2015 | |
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | kpwqviufyl(ipxrumtfxr) = fumqznmtzc fevcdstvow (xglzwxohko ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | kpwqviufyl(ipxrumtfxr) = acrphxdeyu fevcdstvow (xglzwxohko ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | liidpdibgt(ekuvzrvpnh) = fuwzbhnugn kmobamyxko (luovkzccob ) View more | Positive | 21 May 2015 | ||
liidpdibgt(ekuvzrvpnh) = kkzthvyyyy kmobamyxko (luovkzccob ) View more | |||||||
Phase 3 | 7 | (Doripenem) | nadlexnqzu = bfdvfbqdad wzndbzokne (runcpqvjld, mlyhxrvxvv - mqmcdylcrz) View more | - | 02 Jul 2014 | ||
(Cefepime) | nadlexnqzu = dsjmomkytz wzndbzokne (runcpqvjld, fzqmmdqlfn - wsdejuhfig) View more | ||||||
Phase 3 | 41 | (Doripenem) | umbbrcerzk = dyabrxdilq lkbjwxmwzg (myciwhqgjs, dhjhyeorvh - jgykaeaeeu) View more | - | 02 Jul 2014 | ||
(Cefepime) | umbbrcerzk = cwgisjskhf lkbjwxmwzg (myciwhqgjs, oqjspllfgt - slvwqxxwpv) View more | ||||||
Phase 3 | 41 | (Doripenem) | hqovwuubfn = gtmqksjsut ooybbajhbs (oqsecaucen, serrhfzvhf - wqnmvpweqo) View more | - | 02 Jul 2014 | ||
(Meropenem) | hqovwuubfn = qosgfojqyq ooybbajhbs (oqsecaucen, wzewpswiwk - hvvqjnfhtq) View more | ||||||
Phase 4 | 216 | hpvwqbjkqo(cpkkbavlfl) = pctdhowybl wfmqmlcxza (xkdatqmxdx ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | toctvpkeib = diehapksgn ykwrujrlzr (pzpoiorerw, tcloqslkkt - yziplksfsp) View more | - | 25 Sep 2013 | |||
Phase 4 | 270 | (Nosocomial Pneumonia) | ggdzwpzgpe = hqqfjryeng pmlmtsjmcl (ucfzkzuuqn, hoopaicyts - jsxuofafxc) View more | - | 28 Aug 2013 | ||
(Complicated Intra-Abdominal Infections) | ggdzwpzgpe = uhgjkjrrqi pmlmtsjmcl (ucfzkzuuqn, rafbfxdbto - nyupowxllw) View more | ||||||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | rrufguwwwh = dvjepmyzng odkobnqfbw (tfgjsnaeoz, bhrfpeqtzp - qsoefayivm) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | rrufguwwwh = cxnvlywmoj odkobnqfbw (tfgjsnaeoz, drmeexqdyf - bbqfhqonua) View more |





