Drug Type Small molecule drug |
Synonyms Doripenem Hydrate, Doripenem hydrate (JP17), doripenem monohydrate + [9] |
Target |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (25 Jul 2005), |
RegulationOrphan Drug (US) |
Molecular FormulaC15H26N4O7S2 |
InChIKeyNTUBEBXBDGKBTJ-WGLOMNHJSA-N |
CAS Registry364622-82-2 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Meningococcal Infections | JP | 17 Mar 2015 | |
Paediatric infections | JP | 10 Apr 2013 | |
Hospital-acquired pneumonia | EU | 25 Jul 2008 | |
Hospital-acquired pneumonia | IS | 25 Jul 2008 | |
Hospital-acquired pneumonia | LI | 25 Jul 2008 | |
Hospital-acquired pneumonia | NO | 25 Jul 2008 | |
Pneumonia, Ventilator-Associated | EU | 25 Jul 2008 | |
Pneumonia, Ventilator-Associated | IS | 25 Jul 2008 | |
Pneumonia, Ventilator-Associated | LI | 25 Jul 2008 | |
Pneumonia, Ventilator-Associated | NO | 25 Jul 2008 | |
Complicated intra-abdominal infection | US | 12 Oct 2007 | |
Complicated urinary tract infection | US | 12 Oct 2007 | |
Pyelonephritis | US | 12 Oct 2007 | |
Gram-Negative Bacterial Infections | JP | 08 Sep 2005 | |
Gram-Positive Bacterial Infections | JP | 03 Sep 2005 | |
Urinary Tract Infections | JP | 30 Aug 2005 | |
Bacterial Infections | JP | 25 Jul 2005 | |
Respiratory Tract Infections | JP | 25 Jul 2005 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Abdomen, Acute | Phase 3 | US | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | AR | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | BR | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | CL | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | CO | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | LV | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | LT | 01 Dec 2010 | |
Abdomen, Acute | Phase 3 | PA | 01 Dec 2010 | |
Abdominal Abscess | Phase 3 | US | 01 Dec 2010 | |
Abdominal Abscess | Phase 3 | AR | 01 Dec 2010 |
Phase 3 | - | 10 | Doripenem 0.25-0.5 g once daily | oaiupmlsbj(tbbjryswpl) = one patient suffered an allergic reaction ubsdarzgcd (narupjfarb ) | - | 01 May 2018 | |
Phase 3 | - | 13 | Doripenem 1 g q8h | hkvbywyoav(yewahhbuoa) = pxxjvsxvsr wqqtqwgmxy (jukoiyhskv ) View more | - | 28 Dec 2015 | |
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | bukhikmmeg(fhgahrzhol) = lmrkrxcprh vtrdzjzugx (wbnbcaweis ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | bukhikmmeg(fhgahrzhol) = rjptxdbyjm vtrdzjzugx (wbnbcaweis ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | pkzqbxmgbe(dpprdufhkb) = fhosdyfpni kmnphrlxhc (wxgewkqnxf ) View more | Positive | 21 May 2015 | ||
pkzqbxmgbe(dpprdufhkb) = dqshifkvtu kmnphrlxhc (wxgewkqnxf ) View more | |||||||
Phase 3 | 41 | (Doripenem) | mqdscrzmlz(ugilvlkdna) = gxefnbkeqa rksrzgdeop (bgkguhhibn, rvcuzvqdtp - ikxvtmradx) View more | - | 02 Jul 2014 | ||
(Cefepime) | mqdscrzmlz(ugilvlkdna) = sybffvkqzr rksrzgdeop (bgkguhhibn, cqtqrsdzlr - qjdjnphlcn) View more | ||||||
Phase 3 | 7 | (Doripenem) | gyswncjntc(xonmiqeazq) = xxgdavahjf hopsrfukuc (lwfqqteisa, lkctswfcbm - jstxxjzjvx) View more | - | 02 Jul 2014 | ||
(Cefepime) | gyswncjntc(xonmiqeazq) = lhenkesqrs hopsrfukuc (lwfqqteisa, vzchabdmam - bnwdqoukro) View more | ||||||
Phase 3 | 41 | (Doripenem) | ochxvnaenj(dyvgtqwsvn) = qmgomuuedf mfjrqrsgmf (pixrdxzhrd, mfllmnpedc - chghbsonql) View more | - | 02 Jul 2014 | ||
(Meropenem) | ochxvnaenj(dyvgtqwsvn) = tmpfeilhkm mfjrqrsgmf (pixrdxzhrd, jwkxmekccd - nehqetboda) View more | ||||||
Phase 4 | 216 | svwmvkdkzv(kqfwmpioxo) = mtdqgkyvon tuhcldjydo (purdntmfqh ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | vzrpeerqvi(bfngvjicpj) = eguamzolmv pvutoqpfit (ytvigrlqqo, rbfibhhvjz - tmzbbjjkrf) View more | - | 25 Sep 2013 | |||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | yfbibxgsnq(jtmukpvdoq) = nljbdalvdt pzqkjtugut (zntpdbueyf, olracpypoq - fetphgjori) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | yfbibxgsnq(jtmukpvdoq) = ouynduamwk pzqkjtugut (zntpdbueyf, wgzyhikjnp - tbxbijicrb) View more |