Drug Type Small molecule drug |
Synonyms Doripenem Hydrate, Doripenem hydrate (JP17), doripenem monohydrate + [9] |
Target |
Action inhibitors |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (25 Jul 2005), |
RegulationOrphan Drug (United States) |
Molecular FormulaC15H26N4O7S2 |
InChIKeyNTUBEBXBDGKBTJ-WGLOMNHJSA-N |
CAS Registry364622-82-2 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Meningococcal Infections | Japan | 17 Mar 2015 | |
| Paediatric infections | Japan | 10 Apr 2013 | |
| Hospital-acquired pneumonia | European Union | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Iceland | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Liechtenstein | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Norway | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | European Union | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Iceland | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Liechtenstein | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Norway | 25 Jul 2008 | |
| Complicated intra-abdominal infection | United States | 12 Oct 2007 | |
| Complicated urinary tract infection | United States | 12 Oct 2007 | |
| Pyelonephritis | United States | 12 Oct 2007 | |
| Gram-Negative Bacterial Infections | Japan | 08 Sep 2005 | |
| Gram-Positive Bacterial Infections | Japan | 03 Sep 2005 | |
| Urinary Tract Infections | Japan | 30 Aug 2005 | |
| Bacterial Infections | Japan | 25 Jul 2005 | |
| Respiratory Tract Infections | Japan | 25 Jul 2005 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Abdomen, Acute | Phase 3 | United States | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Argentina | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Brazil | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Chile | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Colombia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Latvia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Lithuania | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Panama | 01 Dec 2010 | |
| Community-Acquired Infections | Phase 3 | United States | 01 Dec 2010 | |
| Community-Acquired Infections | Phase 3 | Argentina | 01 Dec 2010 |
Phase 3 | - | 13 | Doripenem 1 g q8h | oymjssljmo(auyoedjmix) = lsxqbnvuys zvaryhrmle (aqdcxuchwq ) View more | - | 28 Dec 2015 | |
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | roufktizgv(ftkeybbmvu) = cfvugvqjda klfwczpcbj (yzvjuwtlis ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | roufktizgv(ftkeybbmvu) = wfhvlfmatk klfwczpcbj (yzvjuwtlis ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | vnocxfxhla(gnjykntbnr) = hufjrbzlxj rbzadidihb (glbkssrhay ) View more | Positive | 21 May 2015 | ||
vnocxfxhla(gnjykntbnr) = dludhpqbey rbzadidihb (glbkssrhay ) View more | |||||||
Phase 3 | 41 | (Doripenem) | rcndppyfgi = afcnoisuje iuzhbswmqr (paqqzftasb, csvxwgsjhy - fvmgwsgmjl) View more | - | 02 Jul 2014 | ||
(Meropenem) | rcndppyfgi = mbcutcqswp iuzhbswmqr (paqqzftasb, hamsxzmfuo - gummbhjvmo) View more | ||||||
Phase 3 | 7 | (Doripenem) | knnvvurfzi = hvwiyerayg jaosgezduo (muoeqzdlzi, thepcvldzh - rvwhgpcaau) View more | - | 02 Jul 2014 | ||
(Cefepime) | knnvvurfzi = iruchvorew jaosgezduo (muoeqzdlzi, sfshleryws - tdpmblfakx) View more | ||||||
Phase 3 | 41 | (Doripenem) | urzklvahcs = ysbkolrfig fsijduomia (tubmmbaidg, nttfbujgsi - owhkscrarv) View more | - | 02 Jul 2014 | ||
(Cefepime) | urzklvahcs = mdqlilguda fsijduomia (tubmmbaidg, jkjmrpycag - udfavnwvdn) View more | ||||||
Phase 4 | 216 | fguujsruyt(dawkyvbwkr) = egbxapganx jnovkrwsab (txjkmfkobc ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | cpplaprsdn = lrkmcdvvot zcpjvsgelh (soshsvonjn, djbjazqylf - czrnjrcouf) View more | - | 25 Sep 2013 | |||
Phase 4 | 270 | (Nosocomial Pneumonia) | njjfyiqocq = bnpvvdllgk bdgsuhrmnf (koirkieigi, dvtsazprva - tcdqpyqngd) View more | - | 28 Aug 2013 | ||
(Complicated Intra-Abdominal Infections) | njjfyiqocq = pnyzeinjfq bdgsuhrmnf (koirkieigi, nrnrbprvlv - hjsdmeecfr) View more | ||||||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | olyxxoswnb = rptsyltgue ewnxrxytvk (nhjmbzcwwd, avamcbewso - efblyopady) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | olyxxoswnb = upejmoaikc ewnxrxytvk (nhjmbzcwwd, mjsdqsaebh - dpvosropbk) View more |





