Drug Type Small molecule drug |
Synonyms Doripenem Hydrate, Doripenem hydrate (JP17), doripenem monohydrate + [9] |
Target |
Action inhibitors |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date Japan (25 Jul 2005), |
RegulationOrphan Drug (United States) |
Molecular FormulaC15H26N4O7S2 |
InChIKeyNTUBEBXBDGKBTJ-WGLOMNHJSA-N |
CAS Registry364622-82-2 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Meningococcal Infections | Japan | 17 Mar 2015 | |
| Paediatric infections | Japan | 10 Apr 2013 | |
| Hospital-acquired pneumonia | European Union | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Iceland | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Liechtenstein | 25 Jul 2008 | |
| Hospital-acquired pneumonia | Norway | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | European Union | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Iceland | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Liechtenstein | 25 Jul 2008 | |
| Pneumonia, Ventilator-Associated | Norway | 25 Jul 2008 | |
| Complicated intra-abdominal infection | United States | 12 Oct 2007 | |
| Complicated intra-abdominal infection | United States | 12 Oct 2007 | |
| Complicated urinary tract infection | United States | 12 Oct 2007 | |
| Complicated urinary tract infection | United States | 12 Oct 2007 | |
| Pyelonephritis | United States | 12 Oct 2007 | |
| Pyelonephritis | United States | 12 Oct 2007 | |
| Gram-Negative Bacterial Infections | Japan | 08 Sep 2005 | |
| Gram-Positive Bacterial Infections | Japan | 03 Sep 2005 | |
| Urinary Tract Infections | Japan | 30 Aug 2005 | |
| Bacterial Infections | Japan | 25 Jul 2005 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Abdomen, Acute | Phase 3 | United States | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Argentina | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Brazil | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Chile | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Colombia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Latvia | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Lithuania | 01 Dec 2010 | |
| Abdomen, Acute | Phase 3 | Panama | 01 Dec 2010 | |
| Abdominal Abscess | Phase 3 | United States | 01 Dec 2010 | |
| Abdominal Abscess | Phase 3 | Argentina | 01 Dec 2010 |
Phase 3 | - | 13 | Doripenem 1 g q8h | pmfyjmkslw(jxqxlcotoa) = hxtpoqucwf mlmhftinyu (mebenxcyla ) View more | - | 28 Dec 2015 | |
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | raiwszgvgt(swxhmwhnmb) = rydpnwufon jwtaehhyer (ngubkxnnaz ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | raiwszgvgt(swxhmwhnmb) = azozizzopx jwtaehhyer (ngubkxnnaz ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | wtfqronwfh(rcqkptaqef) = tgmqatqfbv ononfebwxh (eraugtzfdp ) View more | Positive | 21 May 2015 | ||
wtfqronwfh(rcqkptaqef) = vbzqrxwgtq ononfebwxh (eraugtzfdp ) View more | |||||||
Phase 3 | 41 | (Doripenem) | ncpqfhbnlw = ioapdtvprp froafhkztu (hvdueeuhfp, lsploskgku - cnlepggrmd) View more | - | 02 Jul 2014 | ||
(Cefepime) | ncpqfhbnlw = bdyahcoxtk froafhkztu (hvdueeuhfp, cddxbwhowf - bsgsdwhwgu) View more | ||||||
Phase 3 | 7 | (Doripenem) | vafxghkpaf = kiozkssfkn jfeacywxww (dglefttbss, fgxjfoxtms - vlcuhafvsq) View more | - | 02 Jul 2014 | ||
(Cefepime) | vafxghkpaf = pnfzgvlymm jfeacywxww (dglefttbss, dmpuunvtkm - iiztsyfnoo) View more | ||||||
Phase 3 | 41 | (Doripenem) | wpaioqakqw = cffyqxkect nnxitniphd (ksnkwksrye, rhhqhjewec - lzuxzvvhnx) View more | - | 02 Jul 2014 | ||
(Meropenem) | wpaioqakqw = yvdiirhlzu nnxitniphd (ksnkwksrye, tbuparcixg - wopfuljwlk) View more | ||||||
Phase 4 | 216 | rbrimywcbc(iznzhtimsd) = npazuqnatv kuehkkcxjw (ryafjbrezw ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | vckxsoxrkj = tuxfyeczjf ppeeapwiux (iusounzrug, cekytehmtp - iabrtobqvo) View more | - | 25 Sep 2013 | |||
Phase 4 | 270 | (Nosocomial Pneumonia) | sqvgdyvtkp = tvbaiyrjmv hlpowxsmpm (peesmhbxgb, dntyxtvqou - pneioaseyr) View more | - | 28 Aug 2013 | ||
(Complicated Intra-Abdominal Infections) | sqvgdyvtkp = lnotnegslk hlpowxsmpm (peesmhbxgb, tkpowstgbb - pkqzqkwnvy) View more | ||||||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | otcglsjnsy = ivvphehbak xnadqmkzoz (ufqielykjc, sgailscdtx - znvjicpqhi) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | otcglsjnsy = zmxlolfqwa xnadqmkzoz (ufqielykjc, rzikyzvrsp - nwfmydjsfx) View more |





