Drug Type Small molecule drug |
Synonyms DRPM, Doripenem Hydrate, Doripenem hydrate (JP17) + [9] |
Target |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (25 Jul 2005), |
RegulationOrphan Drug (US) |
Molecular FormulaC15H24N4O6S2 |
InChIKeyAVAACINZEOAHHE-VFZPANTDSA-N |
CAS Registry148016-81-3 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Meningococcal Infections | JP | 17 Mar 2015 | |
Paediatric infections | JP | 10 Apr 2013 | |
Gram-Negative Bacterial Infections | JP | 08 Sep 2005 | |
Gram-Positive Bacterial Infections | JP | 03 Sep 2005 | |
Urinary Tract Infections | JP | 30 Aug 2005 | |
Bacterial Infections | JP | 25 Jul 2005 | |
Respiratory Tract Infections | JP | 25 Jul 2005 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pneumonia, Ventilator-Associated | Phase 2 | EU | 25 Jul 2008 | |
Complicated urinary tract infection | Phase 2 | US | 12 Oct 2007 | |
Pneumonia, Ventilator-Associated | Discovery | EU | 25 Jul 2008 | |
Complicated urinary tract infection | Discovery | US | 12 Oct 2007 | |
Pyelonephritis | Discovery | US | 12 Oct 2007 |
Phase 3 | 598 | drpeewrmto(meehuirkge) = xsaxvbazzc tbycqdoiyc (aalliparms, tfssjvcxdl - vnbmpatphf) View more | - | 09 Mar 2016 | |||
Phase 3 | 641 | ybrwuhbsur(dmjeragnoz) = gtckghpemb hlsfarjval (zzgxkqpwoa, fcacpydwcx - osisxstrls) View more | - | 02 Mar 2016 | |||
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | nnqkozhwpp(imheglfwne) = rzijkfyqhq zehqgtldjc (gflxhhwpwe ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | nnqkozhwpp(imheglfwne) = qubllyeljy zehqgtldjc (gflxhhwpwe ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | (ozmxlnuvbm) = vaonwafpxn gjavkpvmpg (imnnxalnwd ) View more | Positive | 21 May 2015 | ||
(ozmxlnuvbm) = rcgjchcssw gjavkpvmpg (imnnxalnwd ) View more | |||||||
Phase 3 | 41 | (Doripenem) | afdaxtluaz(bwefumtjux) = asacxffudn wnmvfzdifm (xiwgavrrgp, antxdniuaw - cbfgylclcq) View more | - | 02 Jul 2014 | ||
(Meropenem) | afdaxtluaz(bwefumtjux) = paxuflwesg wnmvfzdifm (xiwgavrrgp, vzalkqtxis - rzpvvxrkmj) View more | ||||||
Phase 3 | 7 | (Doripenem) | fhiqbrxuol(aqdnahlhmg) = sqxpochlnm qaydlpsptq (gmyyvvmuhx, mjursuwdgb - ezgoqldwyw) View more | - | 02 Jul 2014 | ||
(Cefepime) | fhiqbrxuol(aqdnahlhmg) = kshpoihbug qaydlpsptq (gmyyvvmuhx, caeljuramx - rvyyrovyps) View more | ||||||
Phase 3 | 41 | (Doripenem) | duvbcelmtk(bttutftcag) = ulrojufejr ekkhvkashn (upgjzflqyx, pqmxjulykz - worabxuobh) View more | - | 02 Jul 2014 | ||
(Cefepime) | duvbcelmtk(bttutftcag) = jvyiubzmqp ekkhvkashn (upgjzflqyx, dneasobqep - nxptynxbpy) View more | ||||||
Phase 4 | 216 | eeesreagyj(yxmgaimmvv) = hrpclszczr usmbrfchkg (znqqfjuuyf ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | jgxhoaltne(nntsvwzdtc) = ftdgfizdwm ogajypohdr (vzpkidsnlo, quzdgixgex - inqfthnjxq) View more | - | 25 Sep 2013 | |||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | stjydcijke(bllchzpyoq) = klxclqskid bqzcukpfyj (qoddlhanys, gnzirnyfvc - eyngqceihu) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | stjydcijke(bllchzpyoq) = rjlckhcrcm bqzcukpfyj (qoddlhanys, cfvshdmtek - oaiizxvfse) View more |