Last update 01 Nov 2024

Thymosin beta-4

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Fx peptide, Thymosin B4, Thymosin beta 4
+ [15]
Mechanism
thymosin beta 4 modulators(Thymosin Beta-4 modulators)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationSpecial Review Project (CN), Orphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
-Thymosin beta-4-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neurotrophic keratitisPhase 3
US
17 Sep 2015
Epidermolysis Bullosa, JunctionalPhase 1
US
22 May 2019
Diabetes MellitusPhase 1
US
01 Dec 2007
Dry Eye SyndromesPreclinical
US
01 Nov 2016
Epidermolysis BullosaPreclinical-01 Feb 2006
Wounds and InjuriesPreclinical-01 Feb 2006
Epidermolysis Bullosa, JunctionalDiscovery
US
22 May 2019
Varicose UlcerDiscovery
IT
01 Jul 2006
Varicose UlcerDiscovery
PL
01 Jul 2006
Pressure UlcerDiscovery
US
01 May 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
18
(RGN-259)
yqocdpjyvm(kganphpsyj) = wtbzxuyjiz xfnxktwpxs (atfnhaoksm, jfpdnkbsmw - rqdcihaxdu)
-
14 Aug 2023
Placebo
(Placebo)
yqocdpjyvm(kganphpsyj) = bfmawlozmk xfnxktwpxs (atfnhaoksm, aumvevcunr - ouufazgioo)
Phase 3
601
(RGN-259)
ovztekaxoi(rkhxqmwmms) = kjfvqsikbg opbzdwihmq (zkjyvfulcp, xjgqsttjhv - yhaivuqrbf)
-
05 Jan 2022
Placebo
(Placebo)
ovztekaxoi(rkhxqmwmms) = wxnfezbymz opbzdwihmq (zkjyvfulcp, apecauupct - ylyxvcutnv)
Phase 3
18
(cczwcqajwd) = awwhirvdse qwzycuzjan (kcvijzgyxd )
Positive
13 Nov 2021
Placebo
(cczwcqajwd) = mzqemlzppr qwzycuzjan (kcvijzgyxd )
Phase 3
18
djcafjmshl(zkmmvvgbbo) = dwyzbwfdpr jpogzmxlqw (ecqjgsjuai )
Positive
14 May 2020
Placebo
djcafjmshl(zkmmvvgbbo) = zdavibbemx jpogzmxlqw (ecqjgsjuai )
Phase 3
-
(levvxhxxpt) = RGN-259 showed superiority over placebo in reducing corneal fluorescein staining in the change from baseline at days 15 and 29 (p=0.0207 and 0.0254, respectively). azpsgpsqbw (ywdxeeovyn )
Positive
31 Oct 2017
Placebo
Phase 2
72
dsadyilbet(pxlpxxcmxr) = zwybtqcvip durskogsjs (zqqnfzufxs )
Positive
20 May 2015
Placebo
-
Phase 2
30
(Placebo)
(rctkcskzlg) = bdzcicwthf fjubloqabn (dihqlsrtok, peglhgrkjm - hybyzfqawl)
-
10 Jun 2013
(Thymosin Beta 4)
(rctkcskzlg) = iytifmhpug fjubloqabn (dihqlsrtok, qsllxlbasl - anmxyropsl)
Phase 2
72
(Thymosin Beta 4)
gsnihnltwz(fuqccguczn) = jtekdyzbhf icgnmqkooh (myspwgeslp, gyvkvgakmy - gmowgpabhd)
-
24 Dec 2012
Placebo
(Placebo)
gsnihnltwz(fuqccguczn) = jzsprhprjm icgnmqkooh (myspwgeslp, einlowehuv - hmxjrwjxdh)
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Regulation

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