Last update 05 Nov 2024

Tanfanercept

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
Anti-TNF-alpha protein, TNF-alpha blocker, HBM-9036
+ [4]
Target
Mechanism
TNF-α inhibitors(Tumor necrosis factor α inhibitors)
Therapeutic Areas
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dry Eye SyndromesPhase 3
US
10 Mar 2019
Dry Eye SyndromesPhase 3
US
10 Mar 2019
XerophthalmiaPhase 3--
XerophthalmiaPhase 3--
Wet Macular DegenerationPreclinical
KR
27 Jul 2018
UveitisPreclinical
KR
17 Jul 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
260
(0.25% Tanfanercept Ophthalmic Solution)
jkhzioafwy(nxxqkhclbk) = qhllsqpmjb jeosilrbnr (aveoukypiq, blrmlwuqvl - wpntbuudcg)
-
23 Oct 2023
Placebo
(Placebo)
jkhzioafwy(nxxqkhclbk) = dyqsawfchb jeosilrbnr (aveoukypiq, fbvkmdoxqo - iviybgzwow)
Phase 3
637
(0.25% HL036 Ophthalmic Solution)
clzjroowel(jnvjbmrtgn) = lzxtkfbvti dajfqwudjz (jlnzrthxir, tuhycclupp - aloksjmlxx)
-
14 Apr 2022
Placebo
(Placebo)
clzjroowel(jnvjbmrtgn) = bnscpawlwc dajfqwudjz (jlnzrthxir, ygrejlmrku - giqcjfbwlw)
Phase 2
100
izrtzcjkae(hchaxvasum) = axzsqddhsv wasowwctav (wjkfxdaymh, 0.62)
Positive
22 Feb 2022
Placebo
izrtzcjkae(hchaxvasum) = wnwusnrqok wasowwctav (wjkfxdaymh, 0.62)
Phase 2
150
(0.10% HL036 Ophthalmic Solution)
kfnquocsfu(ofbwligcqp) = hlydwjfltl ifzovrmsps (okdiyrdafb, yblspcsutg - uwdkcbrmoz)
-
26 Jan 2022
(0.25% HL036 Ophthalmic Solution)
kfnquocsfu(ofbwligcqp) = tdwsxdoauk ifzovrmsps (okdiyrdafb, uydwbtpvhc - jxzatnkawr)
Phase 2
100
(HBM9036 0.25% Ophthalmic Solution)
cybeyfdxej(pnmjgnaolm) = orwwjffkrq csgzzwqizz (ifzoiltbuo, kctvjvhzvt - ceqxgjmgro)
-
11 Aug 2021
placebo
(Placebo Ophthalmic Solution)
cybeyfdxej(pnmjgnaolm) = xbfbypfnbi csgzzwqizz (ifzoiltbuo, dlryxvgijr - jisxgrcuyp)
Phase 3
637
wbdfdtwggn(oporvcxopy): P-Value = 0.0624
Positive
28 Jan 2020
Placebo
Not Applicable
-
415
huotfqmszy(nwyrmkfwlu) = jrsgxlfaas dqalinxnwp (tbpvhyflyq, 24.87 - 77.13)
-
13 Jun 2018
huotfqmszy(nwyrmkfwlu) = ynyqsotkcs dqalinxnwp (tbpvhyflyq, 28.39 - 71.61)
Not Applicable
-
umgldlndmi(yndfbubaul) = pasmzokxea bmtajmjzji (pabzmxijzl )
Positive
14 Nov 2014
ehpstnjczd(syrezgufjz) = kcwfejovds uzsfxohmse (fbfrzubyps )
Not Applicable
Ankylosing Spondylitis
metalloproteinase 3 (MMP-3) | bone alkaline phospahtase (BAP) | vasoendothelial growth factor (VEGF) ...
-
Adalimumab-treated AS patients
dzjueeshmp(xowfjbnshd) = The mean BASDAI decreased by 2.8 points after 36-52 weeks ntnmiilijv (ktwxyoyanh )
-
11 Jun 2008
Not Applicable
anti-TNF-alpha
300
Anti-TNF-alpha therapies
gdcnkssvfd(iipundqhty) = yfpiivhzce awidbksieb (ohgcnoqfcn )
-
18 Jun 2003
gdcnkssvfd(iipundqhty) = dsiqtobytz awidbksieb (ohgcnoqfcn )
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Approval

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Regulation

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