Last update 27 Nov 2024

Atumelnant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CRN 04894, CRN-04894, CRN04894
Mechanism
ACTH receptor antagonists(Melanocortin receptor 2 antagonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC33H42F3N5O3
InChIKeyQJRFBKYETDVAJQ-ZEQKJWHPSA-N
CAS Registry2392970-97-5

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cushing SyndromePhase 2
US
12 Oct 2023
Ectopic ACTH SyndromePhase 2
US
12 Oct 2023
Pituitary ACTH HypersecretionPhase 2
US
12 Oct 2023
Adrenal Hyperplasia, CongenitalPhase 1
US
25 Jan 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
5
fncyekulub(jlzeqsonuh) = 252 mcg (99-293) vs 24 mcg (3.9-51); jpzxqjihcr (pbfqjeygea )
Positive
03 Jun 2024
Phase 1
4
nxitmarwuq(ccycavwtik) = rapid and profound androstenedione reductions within two weeks which were maintained for the duration of therapy, androstenedione reductions ranged from 74% to 99%. vkyiojrqyr (sejflswpzp )
Positive
22 May 2024
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Approval

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Regulation

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