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Last update 11 Nov 2025
HZ-H08905
Last update 11 Nov 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms HZ H08905, HZ-H08905, HZH08905 |
Target |
Action inhibitors |
Mechanism CK1ε inhibitors(casein kinase 1 epsilon inhibitors), PI3Kδ inhibitors(Phosphatidylinositol 3 kinase delta inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Related
5
Clinical Trials associated with HZ-H08905CTR20242024
评价HZ-H08905单药对比西达本胺单药治疗复发/难治外周T细胞淋巴瘤随机、双盲、多中心的III期临床研究
[Translation] A randomized, double-blind, multicenter phase III clinical study evaluating HZ-H08905 monotherapy versus chidamide monotherapy in the treatment of relapsed/refractory peripheral T-cell lymphoma
ChiCTR2500098784
A Double-blineded, Randomized, Multi-center Phase III Clinical Study of HZ-H08905 Versus Chidamide in Patients With Relapsed/Refractory PTCL
CTR20213233
HZ-H08905在复发或难治性非霍奇金淋巴瘤患者的安全性/耐受性及药代动力学的I期临床研究
[Translation] Phase I clinical study of the safety/tolerability and pharmacokinetics of HZ-H08905 in patients with relapsed or refractory non-Hodgkin's lymphoma
100 Clinical Results associated with HZ-H08905
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100 Translational Medicine associated with HZ-H08905
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100 Patents (Medical) associated with HZ-H08905
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100 Deals associated with HZ-H08905
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Peripheral T-Cell Lymphoma | Phase 3 | China | 28 Jun 2024 | |
| Anaplastic Large-Cell Lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Cutaneous T-Cell Lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Enteropathy-Associated T-Cell Lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Extranodal NK-T-Cell Lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Follicular Lymphoma | Phase 2 | China | 10 Nov 2025 | |
| hepatosplenic T-cell lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Large Granular Lymphocytic Leukemia | Phase 2 | China | 10 Nov 2025 | |
| NK-cell lymphoma | Phase 2 | China | 10 Nov 2025 | |
| Primary Cutaneous Anaplastic Large Cell Lymphoma | Phase 2 | China | 10 Nov 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 50 | cwfxodsbmt(nbrlwwhkfh) = neutropenia, leukopenia, elevated alanine aminotransferase, elevated aspartate aminotransferase, thrombocytopenia, pneumonia, anemia, rash, elevated serum creatinine, sinus bradycardia, hyperuricemia, abnormal liver function, hypertriglyceridemia, diarrhea, and dermatitis medicamentosa bcocgpqahc (ybsauipqss ) View more | Positive | 08 Dec 2024 | |||
Phase 1 | 24 | vsphpefxew(acaanhncrh) = TRAEs occurring in ≥10% of patients were neutropenia, leukopenia, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated serum creatinine, thrombocytopenia, elevated blood bilirubin, rash, hypercholesteremia, pneumonia, upper respiratory infection, hyperlipidemia, hypertriglyceridemia, hyperuricemia, anemia, elevated blood lactate dehydrogenase and elevated gamma glutamyl transpeptidase enpozqlbtt (qdvinrbuxe ) View more | Positive | 08 Dec 2024 | |||
Phase 1 | 38 | uvsdvociqz(mvcsybmgzr) = sylaanudyw hsixiyknpd (kjajmwedik ) View more | - | 11 Dec 2023 |
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