Last update 21 Nov 2024

HZ-H08905

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
CK1ε inhibitors(casein kinase 1 epsilon inhibitors), PI3Kδ inhibitors(Phosphatidylinositol 3 kinase delta inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Peripheral T-Cell LymphomaPhase 3
CN
28 Jun 2024
Non-Hodgkin's lymphoma refractoryPhase 1
CN
29 Dec 2021
Recurrent Non-Hodgkin LymphomaPhase 1
CN
29 Dec 2021
B-cell lymphoma recurrentIND Approval
CN
15 Dec 2023
B-cell lymphoma refractoryIND Approval
CN
15 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
50
(olkyajzung) = neutropenia, leukopenia, elevated alanine aminotransferase, elevated aspartate aminotransferase, thrombocytopenia, pneumonia, anemia, rash, elevated serum creatinine, sinus bradycardia, hyperuricemia, abnormal liver function, hypertriglyceridemia, diarrhea, and dermatitis medicamentosa lmzhcxptmp (lotfctbunn )
Positive
08 Dec 2024
Phase 1
24
zyilewukzo(vmjcmsljln) = TRAEs occurring in ≥10% of patients were neutropenia, leukopenia, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated serum creatinine, thrombocytopenia, elevated blood bilirubin, rash, hypercholesteremia, pneumonia, upper respiratory infection, hyperlipidemia, hypertriglyceridemia, hyperuricemia, anemia, elevated blood lactate dehydrogenase and elevated gamma glutamyl transpeptidase oeqxpkxkds (gnjbdmnony )
Positive
08 Dec 2024
Phase 1
38
(sutoctmddb) = cdgorgjbwc slkjaaaceq (wyhopbfmvo )
-
11 Dec 2023
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Approval

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Regulation

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