Last update 27 May 2025

PLB-1003

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PLB 1003, PLB1003
Target
ALK
Action
inhibitors
Mechanism
ALK inhibitors(Anaplastic lymphoma kinase inhibitors)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
ALK positive Non-Small Cell Lung Cancer
Inactive Indication-
Originator Organization
Beijing Purunao Biotechnology Co LtdBeijing Purunao Biotechnology Co Ltd
Active Organization
Beijing Purunao Biotechnology Co LtdBeijing Purunao Biotechnology Co Ltd
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationSpecial Review Project (China)
Login to view timeline

Related

1
Clinical Trials associated with PLB-1003
NCT03130881
/ Unknown statusPhase 1
A Phase I Open-label, Multicenter Dose Escalation Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of PLB1003 in Patients With ALK-positive (ALK+) Advanced Non-small Cell Lung Cancer (NSCLC)
100 Clinical Results associated with PLB-1003
Login to view more data
100 Translational Medicine associated with PLB-1003
Login to view more data
100 Patents (Medical) associated with PLB-1003
Login to view more data
100 Deals associated with PLB-1003
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
ALK positive Non-Small Cell Lung CancerPhase 1
China
Beijing Purunao Biotechnology Co LtdBeijing Purunao Biotechnology Co Ltd
08 Nov 2016
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03130881 (WCLC2019)
ManualManual
Phase 1
Non-Small Cell Lung Cancer
ALK rearrangements
21
tdivrwdixa(kswgffhuyu) = A lipase elevation of DLT event was observed at 250 mg BID heczfdyzyq (huldowwabp )
View more
Positive
07 Sep 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free