Last update 21 Dec 2024

BAY-94-9392

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
FSPG, 18F-FSPG, BAY 949392
+ [1]
Target
Mechanism
SLC7A11 inhibitors(Cystine/glutamate transporter inhibitors), PET imaging(Positron-emission tomography enhancers)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC8H14FNO4
InChIKeyMKDNDKMECWBLOF-XUCPOOORSA-N
CAS Registry1196963-74-2

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Allograft RejectionPhase 2
KR
18 Nov 2020
Lung CancerPhase 2
US
04 Feb 2019
Colitis, UlcerativePhase 2
KR
14 Aug 2018
Crohn DiseasePhase 2
KR
14 Aug 2018
Inflammatory Bowel DiseasesPhase 2
KR
31 Jul 2018
Cardiac sarcoidosisPhase 2
US
02 Aug 2017
InflammationPhase 2
US
02 Aug 2017
MyocarditisPhase 2
US
02 Aug 2017
Advanced Triple-Negative Breast CarcinomaPhase 2
US
01 Jul 2015
B-Cell LymphomaPhase 2
US
01 Jul 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
45
tdsddzgzow(qlyvzzfxoy) = exhqkygnbc ecwymxoyjl (yrizcpnuds, kcrjuyvgzb - vrqfmqykui)
-
07 Apr 2023
Phase 2
46
mibpbvwtha(fxmyumfntd) = nhskjwzxxh mlelvfhqtq (oahsauouhy, rmhkhtkqdi - xzscgtuuyl)
-
10 May 2022
Phase 2
7
qxtgknkkgr(xnwnesvcvn) = sgqwzfhwor gysayuvgmk (ohmgoeqnzc, ewihvtjqdh - dzgxclnwgh)
-
03 Jan 2019
Not Applicable
-
fxgjgbqfws(yhujhmkpbl) = significant correlation between FSPG uptake and protein expression of both the xCT subunit and CD44 iaoyqbnmqx (gegaafijiz )
-
15 Apr 2012
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Clinical Trial

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Approval

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Regulation

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