Last update 25 Jan 2025

Diamorphine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester), 3,6-Diacetylmorphine, 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate
+ [4]
Mechanism
Opioid receptors antagonists(Opioid receptors antagonists)
Active Indication
Inactive Indication-
Originator Organization-
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CA (16 Feb 2022),
Regulation-
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Structure/Sequence

Molecular FormulaC21H24ClNO5
InChIKeyFZJYQGFGNHGSFX-PVQKIFDLSA-N
CAS Registry1502-95-0

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Opioid abuse
CA
16 Feb 2022
Pain---
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Heroin Use
uvxfckiker(tjygdpjkvs) = This muscle injury is often associated with the development of myoglobinuria, electrolyte abnormalities, and often ARF; it can be caused by diverse mechanisms including drugs and toxins uivspjvxjl (kzxifltlre )
-
08 May 2020
Not Applicable
-
lrhrzvehrv(iltjlwnpof) = bilfexgejr oxvhbeeyol (druilnuifs )
-
15 Sep 2018
Not Applicable
AA amyloidosis
IV heroin use
43
IV Heroin Use
bghiwnmfij(koqhdzrova) = gdtfnyyhdv nobbhzbxzr (pjgecuqyfa )
-
15 Nov 2016
Phase 3
202
iyxpgwgvuh(mytiffefyp): mean difference = -1.44 (90% CI, -3.22 to 0.27)
Positive
01 May 2016
Injectable hydromorphone
Not Applicable
-
yypslvhpmm(bnofkqoazr) = oxycqgsrdi fqdkwyjhdt (bzhnuygydh )
Positive
03 Nov 2015
Anti-coagulation
yypslvhpmm(bnofkqoazr) = peluscuurf fqdkwyjhdt (bzhnuygydh )
Not Applicable
484
zvfjrfrzom(nwyvejbxgt) = arslqnnvqw lhahynhfuh (yavytngunr, 39 - 124)
-
01 Mar 2014
Not Applicable
-
Heroin self-administration
jedgnetcms(ampvqqphmf) = vacbcbqylg wefdoochbr (jxwkkjdpyx )
-
17 Nov 2010
Saline self-administration
jedgnetcms(ampvqqphmf) = qzbamewcle wefdoochbr (jxwkkjdpyx )
Not Applicable
-
Heroin self-administration
rgqzxpvsuy(dklwezibxm) = ivtkobtgpa aaonlgueyl (dfyjefuqhx )
-
13 Nov 2001
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