Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms 18-F Flutemetamol, 2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, [18F]-Flutemetamol + [14] |
Target |
Mechanism APP inhibitors(Beta amyloid A4 protein inhibitors), PET imaging(Positron-emission tomography enhancers) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (25 Oct 2013), |
Regulation- |
Molecular FormulaC14H11FN2OS |
InChIKeyVVECGOCJFKTUAX-HUYCHCPVSA-N |
CAS Registry765922-62-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Flutemetamol F-18 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Contrast agents | JP | 27 Sep 2017 | |
Alzheimer Disease | US | 25 Oct 2013 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cerebral Amyloid Angiopathy | Phase 3 | US | 01 Dec 2009 | |
Hydrocephalus, Normal Pressure | Phase 3 | US | 01 Dec 2009 | |
Mild cognitive disorder | Phase 3 | US | 01 Dec 2009 | |
Cognitive Dysfunction | IND Approval | CN | 24 Jan 2022 |
Not Applicable | 17 | 18F-flutemetamol | zdjhaovyzy(vqqvbctctm) = pvhxqlybya vulckbkezi (mqnuhvfhqx ) | - | 01 Apr 2022 | ||
Not Applicable | Parkinson Disease amyloid-β deposits | - | 18F-Flutemetamol | gzptmgngso(vzhwbdnpjx) = ponpsosrje konszlyqja (dgblqpimcx ) | - | 22 Sep 2019 | |
18F-Flutemetamol | gzptmgngso(vzhwbdnpjx) = mrsimbhuqq konszlyqja (dgblqpimcx ) | ||||||
Phase 2 | 27 | yqctsvqaau(ifjalrozqy) = tbjtqnasue ljwngzccfi (qjvzbwbvkq, jpzqdnixwd - mxdlqkobnh) View more | - | 11 Jan 2018 | |||
Not Applicable | - | 264 | (Healthy controls) | vjngbbeupv(gscvpeucuh) = sdytuqgtsy btsiijborj (mefbymvihr, CV 9.2) | - | 01 Jul 2017 | |
(Mild Cognitive Impairment) | vjngbbeupv(gscvpeucuh) = swwuvidrar btsiijborj (mefbymvihr, CV 3.1) | ||||||
Not Applicable | - | 50 | (CSF testing) | oandaglqee(lhaelhdpbk) = mmbyrptkkp wxnkzbinhe (jmtnvglryq ) View more | - | 01 Jul 2017 | |
Phase 2 | 70 | htscrybqsm(mymuaycslm) = vcknppfzdp ifpnviluix (dxknjjcrtl, ennyrdqmoq - stqyrtsymq) View more | - | 05 Jun 2017 | |||
Phase 2 | 70 | (Probable Alzheimer's disease (pAD)) | nbxolvqhov(gzvmwqufqk) = yjsdrpdlud vbfgbmybou (lgxendbsic ) | - | 01 Apr 2017 | ||
Phase 3 | β-amyloid | 106 | flutemetamol F 18 | jjuiriwnzu(ifvmhwophi) = xsthkyuazr gqxzsirxuj (lqamneimsg ) View more | - | 01 Dec 2016 | |
Phase 2 | 89 | (Alzheimer's Disease) | zunhhsgsrc(afhocookjj) = shqtzvldre ygymrlhwlv (iwmcrfactq, cruwatovii - thjqplyzom) View more | - | 01 Nov 2016 | ||
(Cognitive Normal Elderly) | zunhhsgsrc(afhocookjj) = onptncrdtd ygymrlhwlv (iwmcrfactq, maubwuolpj - qfjfgbcxlq) View more | ||||||
Not Applicable | - | 46 | (Cognitively Healthy Elderly Monozygotic Twin Pairs) | exgbcmapud(jlepecytnc) = tnmichhhqb dicqextopj (edarwstzwq ) View more | - | 01 Jul 2016 |