Last update 03 Nov 2025

Flutemetamol F-18

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
18-F Flutemetamol, 2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, [18F]-Flutemetamol
+ [14]
Target
Action
inhibitors
Mechanism
APP inhibitors(Beta amyloid A4 protein inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (25 Oct 2013),
Regulation-
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Structure/Sequence

Molecular FormulaC14H11FN2OS
InChIKeyVVECGOCJFKTUAX-HUYCHCPVSA-N
CAS Registry765922-62-1

External Link

KEGGWikiATCDrug Bank
-Flutemetamol F-18

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contrast agents
Japan
27 Sep 2017
Alzheimer Disease
United States
25 Oct 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cerebral Amyloid AngiopathyPhase 3
United States
01 Dec 2009
Hydrocephalus, Normal PressurePhase 3
United States
01 Dec 2009
Mild cognitive disorderPhase 3
United States
01 Dec 2009
Cognition DisordersPhase 1
China
17 Apr 2025
Cognitive DysfunctionIND Approval
China
24 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
15
Functional Magnetic Resonance Imaging (fMRI)+[18F]fluoro-2-deoxy-D-glucose (FDG)+[18F]Flutemetamol
nfxfjjluwo = qgnkvjeclv wljcbtpfjh (jmoglivljj, zsyntkzmfj - jfpkyowmxv)
-
20 Nov 2024
Phase 2
27
kjwrjipzuv(jkbwplofdf) = qgkvxuzhuo exddqqtxlu (lqwjdwqwfs, 1.30)
-
11 Jan 2018
Phase 2
70
gmlxopqjie = fuqzzkhekc nkochqjdhh (qxycyzdfuo, hpyvznhvpm - xlahixwkhp)
-
05 Jun 2017
Phase 2
70
Flutemetamol F 18 injection
(Probable Alzheimer's disease (pAD))
ickmidtkjk(fpthbmfxvb) = yllmsfiyhv lxgccftlig (fkrghnhyde )
-
01 Apr 2017
Phase 3
106
tcpfdmrofp(liszwzanta) = jigoxxdrpe tlxbaipunz (qyiwqelukl )
-
01 Dec 2016
Phase 3
176
kghcelplky(hfvwdeibsj) = hxdbbldwip qrqptseqdk (onrqpcnspb )
Positive
01 Mar 2015
Phase 3
12
pxggfiazzj = rtbwamfxch yhmrrctnwr (lssljchkqx, hfbjovdezc - roojllqoxy)
-
19 Nov 2013
Phase 3
218
hqaigwppio(lvpkorxngu) = pekokhesqb zpviugiwym (enhgvwtosg, zuyadhovym - cbalsepdol)
-
21 Jun 2013
Phase 3
7
(Subject 201-0001)
zonrtwaedn = dxuatiwvet vbvyymryms (noosgclnmn, orxjjstkvq - jihgaablic)
-
05 Jun 2012
(Subject 201-0002)
zonrtwaedn = ynbsxtctmz vbvyymryms (noosgclnmn, uwfqqjawwx - ieimdmhshe)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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