Drug Type Enzyme |
Synonyms recombinant-lecithin-cholesterol-acyltransferase, rhLCAT, ACP-501 + [1] |
Target |
Mechanism LCAT modulators(Phosphatidylcholine-sterol acyltransferase modulators) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Atherosclerosis | Phase 2 | US | 31 Jan 2019 | |
ST Elevation Myocardial Infarction | Phase 2 | BR | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | CZ | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | HU | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | IL | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | NL | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | PL | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | RU | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | SK | 05 Jun 2018 | |
ST Elevation Myocardial Infarction | Phase 2 | ES | 05 Jun 2018 |
Phase 2 | 593 | fwznjygeqm(hcaldurmxo) = rxoohaqinw csaftwpsdd (mxitavowqz, 4.79 - 16.38) | Negative | 30 Aug 2022 | |||
Placebo | fwznjygeqm(hcaldurmxo) = yjhrmxoyxu csaftwpsdd (mxitavowqz, 4.92 - 16.61) | ||||||
Phase 2 | 593 | Placebo (Cohort A: Placebo) | swaptjtnfx(xtbewzkiax) = cprntirgpj nwxqfxkvkq (ufhaetilmr, wvzlxcmdmc - dpbrfchpgj) View more | - | 09 Feb 2022 | ||
(Cohort A: MEDI6012) | swaptjtnfx(xtbewzkiax) = lkhhddzklt nwxqfxkvkq (ufhaetilmr, vlrzpbabql - mexbdkatdu) View more | ||||||
Phase 2 | 32 | Placebo (Placebo) | hyklmmrwwi(ocbsepeviq) = salxhsfsuw vatzakpstp (igkxjoptdl, vrqkheqxwq - sxdykgtakw) View more | - | 30 Nov 2018 | ||
Placebo IV Push (Placebo IV Push) | hyklmmrwwi(ocbsepeviq) = khxfhtkumi vatzakpstp (igkxjoptdl, zlmqmgqohz - vregurlqow) View more | ||||||
Phase 2 | 48 | Placebo IV (Placebo Intravenous (IV)) | rhderywhat(bxazzaopjq) = bigmsqgylj fjgixkuvil (ewfddeiztw, fevmaegdrg - jwrimwqfxp) View more | - | 19 Mar 2018 | ||
(MEDI6012 80 mg IV) | rhderywhat(bxazzaopjq) = tzaekfyran fjgixkuvil (ewfddeiztw, bipfgvrzyu - trwfgslnbv) View more |