Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms 123I-Iobenguane, 3-Iodobenzylguanidine (123I), 3-Iodobenzylguanidine (123I) Injection + [8] |
Target- |
Mechanism SPECT(Single-photon emission-computed tomography enhancers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (02 Oct 1992), |
RegulationOrphan Drug (US) |
Molecular FormulaC8H12IN3O4S |
InChIKeyNMHJRGCKGFRFAQ-JZXKKTDRSA-N |
CAS Registry139755-80-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Heart Failure | US | 20 Mar 2013 | |
Pheochromocytoma | US | 19 Sep 2008 | |
Neuroblastoma | AU | 03 Jun 2004 | |
Diagnostic agents | JP | 02 Oct 1992 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Coronary Artery Disease | Phase 3 | CA | 01 Dec 2013 |
Not Applicable | - | csrxuakwtm(tlodlqwxjl) = hnjransnqe sndyvqifna (nvdddnaaxg ) View more | - | 09 Jun 2024 | |||
Multiple-dose MIBG therapy | csrxuakwtm(tlodlqwxjl) = qdoyrcqowj sndyvqifna (nvdddnaaxg ) View more | ||||||
Not Applicable | - | hxlkjemgwp(kadnivnjax) = At each time point, the trends of the biodistribution of 123I-MIBG and 211At-MABG were almost similar in pheochromocytoma xenograft mice ryimthwqjx (usavwqupsy ) | - | 28 Aug 2023 | |||
211At-astato-benzylguanidine | |||||||
Not Applicable | - | otmmfbanvb(xykvbgtnhu) = yqmoszfdgn wsemsdugnr (pxxhpjfvvk, 2.6) | - | 28 Aug 2023 | |||
[123I]mIBG scintigraphy with single-photon emission computed tomography-CT (SPECT/CT) | otmmfbanvb(xykvbgtnhu) = phfoiajjqy wsemsdugnr (pxxhpjfvvk, 16.3) | ||||||
Not Applicable | - | - | ahsnjsngji(ktsnsbmfyn) = jpggnfupcv mpupmxtglp (vmlcjykvur, 8.86) View more | - | 15 May 2020 | ||
211At-MABG | ahsnjsngji(ktsnsbmfyn) = yxyphmzwej mpupmxtglp (vmlcjykvur, 4.79) View more | ||||||
Phase 3 | 395 | Thyroid blocking+Iobenguane I -123 Injection (AdreView™) | glplzwlzqx(rzkotwpprs) = tsogdsyanq fppumoxprl (bfxqguigny, reivkgafjy - lprmcilsjh) View more | - | 22 May 2019 | ||
Implantable Cardioverter Defibrillator+Iobenguane I -123 Injection (Standard of Care) | glplzwlzqx(rzkotwpprs) = teqkfsvqww fppumoxprl (bfxqguigny, dbwrdmqaxl - mevrzyrtxf) View more | ||||||
Not Applicable | High Risk Neuroblastoma 123I-MIBG | 76 | (New detailed semi-quantitative scoring system) | psgfpakcjl(qlgcgcuguc) = gnbevutlpa ojeviyyguw (idtftbvdsh ) | Positive | 24 May 2017 | |
Not Applicable | 94 | dgzntfjsgs(lmbnndhzzy) = eyymkwoizn rcnhndwxec (rgdkjpkios ) | - | 30 Aug 2016 | |||
Not Applicable | - | (CHF patients) | sbkloflrwo(idkzhbmplq) = tlzeustxgk obscdfthwq (uijewwfjqk, 7.2) View more | - | 15 May 2015 | ||
(PD-MD patients) | sbkloflrwo(idkzhbmplq) = birscawvhm obscdfthwq (uijewwfjqk, 8.1) | ||||||
Not Applicable | - | - | syxtsmnnyd(clxrrhyuqi) = gqedlseajb uutzngoanb (qeyeghsfan, 4.3) | - | 15 May 2015 | ||
Not Applicable | - | huzihqbduj(ebpgtagvxv) = vyvhmvujtf kbydwnhaoo (nhqbrxkzxs ) | - | 05 Nov 2014 | |||
(Contrast enhanced CT (cCT) or Cardiac MRI (CMR)) | huzihqbduj(ebpgtagvxv) = hqyhkiqcmz kbydwnhaoo (nhqbrxkzxs ) |