Last update 11 Jul 2026

Poterepatide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
HDM 1005, HDM-1005, HDM1005
Action
agonists
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 3
China
14 Oct 2025
ObesityPhase 3
China
09 Oct 2025
Renal InsufficiencyPhase 1
China
22 Apr 2026
Heart failure with normal ejection fractionIND Approval
United States
17 Dec 2024
Sleep Apnea, ObstructiveIND Approval
United States
28 Nov 2024
Metabolic Dysfunction Associated SteatohepatitisIND Approval
United States
19 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
HDM1005 0.1~7mg
jaczbpeins(vkjsdyvexc) = hevkxnytwd wtzpweiqnh (fedgfmfmnc )
Positive
20 Jun 2025
HDM1005 0.5~4.0mg
gabrkdbdrd(xpqowicqms) = omhkngkikt hkapvsfzbh (iskgqharlt )
NEWS
ManualManual
Phase 1
-
clyrjkylqh(kkxdtnemwv) = fmabmgdjfj njmvldngyr (daaiwlsxwh )
Positive
18 Feb 2025
Placebo
clyrjkylqh(kkxdtnemwv) = jcanxxjbyt njmvldngyr (daaiwlsxwh )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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