Last update 21 Feb 2026

DLL3 ASPIRE-T (TCRCure)

Overview

Basic Info

Drug Type
CAR-T
Synonyms
TC D101, TC-D101, TCD101
Target
DLL3
Action
inhibitors
Mechanism
DLL3 inhibitors(Delta-like protein 3 inhibitors)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
DLL3 positive Small Cell Lung CancerSmall Cell Lung Cancer
Inactive Indication-
Originator Organization
Guangdong TCRCure Biopharma Technology Co. Ltd.Guangdong TCRCure Biopharma Technology Co. Ltd.
Active Organization
Guangdong TCRCure Biopharma Technology Co. Ltd.Guangdong TCRCure Biopharma Technology Co. Ltd.Beijing TCRcure Biotechnology Co., LtdBeijing TCRcure Biotechnology Co., Ltd
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with DLL3 ASPIRE-T (TCRCure)
NCT07246304
/ RecruitingEarly Phase 1
A Preliminary Exploratory Clinical Study of TC-D101 in the Treatment of DLL3-Positive Relapsed/Refractory Primary Small Cell Lung Cancer
100 Clinical Results associated with DLL3 ASPIRE-T (TCRCure)
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100 Translational Medicine associated with DLL3 ASPIRE-T (TCRCure)
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100 Patents (Medical) associated with DLL3 ASPIRE-T (TCRCure)
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100 Deals associated with DLL3 ASPIRE-T (TCRCure)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
DLL3 positive Small Cell Lung CancerPhase 1
China
Guangdong TCRCure Biopharma Technology Co. Ltd.Guangdong TCRCure Biopharma Technology Co. Ltd.
30 Nov 2025
Small Cell Lung CancerPhase 1
China
Beijing TCRcure Biotechnology Co., LtdBeijing TCRcure Biotechnology Co., Ltd
17 Nov 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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