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Last update 14 Nov 2025
SIM-1803-1A
Last update 14 Nov 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms SIM 18031A, SIM1803 1A, SIM1803-1A |
Target |
Action inhibitors |
Mechanism ALK inhibitors(Anaplastic lymphoma kinase inhibitors), ROS1 inhibitors(Proto-oncogene tyrosine-protein kinase ROS inhibitors) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |
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Related
1
Clinical Trials associated with SIM-1803-1ANCT04671849
An Open Label, Multi-center, Phase I Clinical Study to Evaluate the Safety, Effectiveness and Pharmacokinetic Characteristics of SIM1803-1A in Patients With Locally Advanced/Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion Mutations.
100 Clinical Results associated with SIM-1803-1A
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100 Translational Medicine associated with SIM-1803-1A
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100 Patents (Medical) associated with SIM-1803-1A
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100 Deals associated with SIM-1803-1A
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| ALK fusion Positive Solid Tumors | Phase 1 | China | 21 Dec 2020 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | China | 21 Dec 2020 | |
| NTRK fusion-positive solid tumors | Phase 1 | China | 21 Dec 2020 | |
| ROS1 positive Solid Tumors | Phase 1 | China | 21 Dec 2020 | |
| Solid tumor | Phase 1 | China | 21 Dec 2020 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Not Applicable | 22 | drcrhdrwxu(ewewrmilhz) = 丙氨酸氨基转移酶升高(22.7%) azhulluwfl (araggqllsx ) View more | - | 21 Sep 2022 |
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