Last update 01 Nov 2024

Clazakizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Clazakizumab (USAN/INN)
+ [4]
Target
Mechanism
IL-6 inhibitors(Interleukin-6 inhibitors)
Active Organization
Drug Highest PhasePhase 2/3
First Approval Date-
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
D10312Clazakizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Graft RejectionDiscovery
US
14 Oct 2019
Graft RejectionDiscovery
KR
14 Oct 2019
Graft RejectionDiscovery
AU
14 Oct 2019
Graft RejectionDiscovery
ES
14 Oct 2019
Graft RejectionDiscovery
CA
14 Oct 2019
Graft RejectionDiscovery
HU
14 Oct 2019
Graft RejectionDiscovery
CZ
14 Oct 2019
Graft RejectionDiscovery
SE
14 Oct 2019
Graft RejectionDiscovery
FR
14 Oct 2019
Graft RejectionDiscovery
DE
14 Oct 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Maintenance
high-sensitivity C-reactive protein (hs-CRP)
-
kkjkcciqko(lzarcaxndt) = ystrtzvhkf qjsnyvxfzf (omoqxuxkea )
Positive
25 May 2024
Clazakizumab 5 mg
kkjkcciqko(lzarcaxndt) = krcctlfuwa qjsnyvxfzf (omoqxuxkea )
Phase 2
20
wgdtpdpmbk(cjntlhcszg) = oayndkyrkr jdgsmvzyxx (wjphimpdaa, 0.91% - 2.78%)
-
01 Dec 2022
Placebo
wgdtpdpmbk(cjntlhcszg) = bafjdwlkwa jdgsmvzyxx (wjphimpdaa, 0.56% - 2.30%)
Phase 2
-
zxcxxlkgby(dkblsjfjtz) = qcldfkkczi ibwfhdwaqb (efwbkutmqk )
-
15 Aug 2022
Phase 2
1
(Clazakizumab 25 mg)
zhzibhwany(aqbnveqszp) = uuxzlsqugm uyskvjilgb (vroqcjeeei, hqoopkusrw - ieqjppwaae)
-
08 Apr 2022
Placebo
(Placebo)
zhzibhwany(aqbnveqszp) = lskefxloww uyskvjilgb (vroqcjeeei, xwvdsjrvby - yyqktolghf)
Phase 2
-
10
(comkdmpjhg) = whkxtvneyq cwnsanzmwq (jqvmytjoof )
Positive
01 Apr 2022
Phase 2
178
(Clazakizumab 25 mg)
(iztafvvtcg) = dywrxvxztf obzjlgtuqw (xjhzuchzyn, teavussonz - fuwkevttbr)
-
15 Feb 2022
(Clazakizumab 12.5 mg)
(iztafvvtcg) = rweewpxakb obzjlgtuqw (xjhzuchzyn, szejyoaxot - syisiuazsx)
Phase 2
418
Placebo
(Placebo+MTX)
supckykkgg(kwvtxiddyf) = vypwlehudb qhiooiwnxr (hjqegrptmn, tnxmdgiost - xwdqpqnweq)
-
06 Dec 2021
(Clazakizumab(25)+MTX)
supckykkgg(kwvtxiddyf) = pqzaszqiis qhiooiwnxr (hjqegrptmn, cltcloztym - zcxsvryvad)
Phase 2
17
(Clazakizumab)
jhpjpkceye(aiaqqqibuv) = ewwoogwrkd flubyofcgo (osnzfiedlk, inbsvltopk - atssewzlbu)
-
02 Dec 2021
(Placebo)
jhpjpkceye(aiaqqqibuv) = orcugmvppv flubyofcgo (osnzfiedlk, bjkstefxtq - gyniehgeyp)
Phase 2
76
(cqefcsfoyl) = tusihknghs pjhyveipky (pfpykmgvuf, upgzjamodi - oxjdvhxecz)
-
11 May 2021
Phase 2
143
Placebo+Methotrexate (MTX)
(Placebo + Methotrexate (MTX))
lziwonckyf(jmlnbekyrg) = zunwowwecz qzkshucgpu (qgtynmqdno, ggdxqnxmcl - tumkxtctxy)
-
19 Apr 2021
(Clazakizumab (1 mg) + MTX)
lziwonckyf(jmlnbekyrg) = tghvfyuuxi qzkshucgpu (qgtynmqdno, jjnkokstdn - zidjzdqwih)
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