Last update 08 May 2025

AST-0555

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
EIF2AK1 x EIF2AK4 x PERK
Action
inhibitors
Mechanism
EIF2AK1 inhibitors(eukaryotic translation initiation factor 2 alpha kinase 1 inhibitors), EIF2AK4 inhibitors(eukaryotic translation initiation factor 2 alpha kinase 4 inhibitors), PERK inhibitors(eukaryotic translation initiation factor 2 alpha kinase 3 inhibitors)
Therapeutic Areas
NeoplasmsCongenital DisordersDigestive System Disorders+ [3]
Active Indication
Anemia, Sickle CellPancreatic Ductal AdenocarcinomaSarcoma
Inactive Indication-
Originator Organization
Aston SCIAston SCI
Active Organization
Aston SCIAston SCI
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with AST-0555
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100 Translational Medicine associated with AST-0555
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100 Patents (Medical) associated with AST-0555
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100 Deals associated with AST-0555
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia, Sickle CellDiscovery
South Korea
Aston SCIAston SCI
01 Mar 2025
Pancreatic Ductal AdenocarcinomaDiscovery
South Korea
Aston SCIAston SCI
01 Mar 2025
SarcomaDiscovery
South Korea
Aston SCIAston SCI
01 Mar 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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