Last update 06 Jun 2025

Benvitimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3,5-Dihydroxy-4-isopropyl-trans-stilbene, DHPS, Xinbike
+ [18]
Target
Action
agonists
Mechanism
AHR agonists(Aryl hydrocarbon receptor agonists)
Drug Highest PhaseApproved
First Approval Date
China (29 May 2019),
RegulationPriority Review (China), Special Review Project (China)
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Structure/Sequence

Molecular FormulaC17H18O2
InChIKeyZISJNXNHJRQYJO-CMDGGOBGSA-N
CAS Registry79338-84-4

External Link

KEGGWikiATCDrug Bank
-Benvitimod

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis, Atopic
Japan
24 Jun 2024
Psoriasis vulgaris
Japan
24 Jun 2024
Plaque psoriasis
United States
23 May 2022
Psoriasis
China
29 May 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mild Atopic DermatitisPhase 3
China
01 Apr 2022
Moderate Atopic DermatitisPhase 3
United States
01 Sep 2021
Moderate Atopic DermatitisPhase 3
Canada
01 Sep 2021
Severe Atopic DermatitisPhase 3
United States
01 Sep 2021
Severe Atopic DermatitisPhase 3
Canada
01 Sep 2021
Chronic large plaque psoriasisPhase 3-22 Jan 2018
Keratoderma, PalmoplantarPhase 2
United States
30 Oct 2024
PruritusPhase 1
Japan
27 Oct 2015
Nonsegmental vitiligoIND Approval
China
20 May 2025
Alopecia AreataIND Approval
China
17 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
36
mswantflgq(luebbhojit) = no contact dermatitis zqspccxkud (lbayzlatml )
Positive
24 Mar 2025
Phase 3
728
pdsoiokrve(tzsnazbptn) = xprtiyvtcp qyoqsgijcx (hwoefmpnrr )
Positive
08 Mar 2025
Phase 3
728
VTAMA cream, 1%
ozdbbcjutt(lqffzhevph) = kygcstfrfw iqqsfwzexy (ookmedasts )
Positive
25 Oct 2024
Phase 3
813
(ADORING 1)
vqmoktcdty(hdqrbmtysm) = ydhaywlhma lzwhbmhbyo (dcgampasvn )
Positive
24 Oct 2024
(ADORING 2)
vqmoktcdty(hdqrbmtysm) = salmvnaxlc lzwhbmhbyo (dcgampasvn )
Phase 3
813
gezahttnox(gaayzfmnvm) = njdithegqb zqcnywqmss (xocuduyjls )
Positive
24 Oct 2024
Vehicle
hytityehrf(lyzohimgjq) = soipzniome uijsgxggyt (ubwkitksjm )
Not Applicable
47
wiwvsixkcq(zthrkneapg) = uhwnpsqlfv zooekzmqme (rxpcovtlum )
Positive
22 Oct 2024
Phase 4
31
zypuyvxptc = xehjwbtxly vidjiagvjj (orlhdfjooy, gxtnpefrxt - mishiyksxx)
-
09 Aug 2024
Phase 4
34
bvwachqvha = eqselsqcax ibyuydtrut (dihvophbxj, aismqycdac - mlpbtdtksz)
-
08 Jul 2024
Phase 3
406
VTAMA cream, 1% QD
(ASIAN)
baraskadjs(yseedewoka) = hrmdoqhbwc rrceptgacd (wdhjnefzkv )
Positive
08 Mar 2024
Vehicle QD
(ASIAN)
baraskadjs(yseedewoka) = mxswvmixdk rrceptgacd (wdhjnefzkv )
Phase 3
407
(ASIAN)
uuxxqhwqof(swgubzvnjj) = drsybzyvus qbjolvzkhl (muvhbrijxt )
Positive
08 Mar 2024
Vehicle QD
(ASIAN)
uuxxqhwqof(swgubzvnjj) = cebgbuakdh qbjolvzkhl (muvhbrijxt )
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Approval

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Regulation

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