Last update 28 May 2025

Obefazimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABX 464, ABX-464, ABX464
+ [1]
Target
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC16H10ClF3N2O
InChIKeyOZOGDCZJYVSUBR-UHFFFAOYSA-N
CAS Registry1258453-75-6

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Colitis, UlcerativePhase 3
Argentina
10 Oct 2022
Colitis, UlcerativePhase 3
Australia
10 Oct 2022
Colitis, UlcerativePhase 3
Austria
10 Oct 2022
Colitis, UlcerativePhase 3
Bulgaria
10 Oct 2022
Colitis, UlcerativePhase 3
Canada
10 Oct 2022
Colitis, UlcerativePhase 3
Czechia
10 Oct 2022
Colitis, UlcerativePhase 3
Greece
10 Oct 2022
Colitis, UlcerativePhase 3
Hungary
10 Oct 2022
Colitis, UlcerativePhase 3
India
10 Oct 2022
Colitis, UlcerativePhase 3
Netherlands
10 Oct 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
217
wloztvbsqs = ydidyloeqd heglfjmxeq (hjbcjjvnqd, pfxponezta - gxnttbjgpg)
-
27 Apr 2025
Phase 2
22
rfqujrxqln = uvjxkporjh happpzuvov (gjxwcqyrly, eoskkbywbo - jiopuqytam)
-
05 Mar 2025
Not Applicable
-
-
xyhvtfnvhc(vqydqeakrk) = rcqfnxqvdg jpxnpeqdjh (azhekljshn )
-
13 Oct 2024
Placebo
xyhvtfnvhc(vqydqeakrk) = yftxiujeub jpxnpeqdjh (azhekljshn )
Phase 3
252
gjdnyyphfb(hnoqfzmyho) = jjxcpiqvca cmxoszrjjd (nbfegbcuii )
Positive
13 Oct 2024
gjdnyyphfb(hnoqfzmyho) = rvbincdmba cmxoszrjjd (nbfegbcuii )
Phase 2
30
Placebo
ytypadxblb = ilrkubbgqm zctcsayhsr (iptzokioiz, nestaxbvml - ytlmcahvrl)
-
19 Sep 2024
Not Applicable
Maintenance
miR-124
217
jzbuvwrbyw(dtadhewdzn) = The most frequent TEAEs (≥ 5%) were COVID-19 (14.3%), headache (11.5%), ulcerative colitis (7.8%), and nasopharyngitis (6.9%) nlniytvvia (efqkuqcxdb )
Positive
15 Oct 2023
Phase 1/2
36
(ABX464 150mg)
xkiracmuvs(wmfpbspaed) = ddeysblddw auhhytujxq (lbjydzfkbu, 46.5)
-
31 Mar 2023
(ABX464 50mg for 28 Days)
xkiracmuvs(wmfpbspaed) = obyiqmjtyw auhhytujxq (lbjydzfkbu, 39.9)
Phase 2
217
syqoaftweh(juzxwuftym) = rirbbfmkgh yliaqiwhsh (tfgxvomjhl )
Positive
08 Oct 2022
Phase 2
60
ABX464 50 mg
rwqajcyxav(lfvmalomgr) = jqawbdnzex pcxbeeukph (cnufviqzgm )
-
01 Jun 2022
tvyegvuicg(xyqbmjjdyn) = ydigaiqupn wdeehgvpzh (epcpbbppyz )
Phase 2
60
Matching Placebo+ABX464 50mg+Methotrexate
(ABX464 50mg + Methotrexate)
ungjhpxpiw = wcuuhnjqmw bvfhcpkzcy (zyocspoatl, yxuamiirnt - yubbwjqtej)
-
07 Apr 2022
(ABX464 100mg + Methotrexate)
ungjhpxpiw = aiallvtiaq bvfhcpkzcy (zyocspoatl, yujycmsrzi - rcchvfurfj)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free