Drug Type Small molecule drug |
Synonyms Olumacostat glasaretil (USAN/INN) + [2] |
Target |
Mechanism ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC26H43NO7 |
InChIKeyFYJLDICZGDFWKP-UHFFFAOYSA-N |
CAS Registry1261491-89-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acne Vulgaris | Phase 3 | CA | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | US | 27 Dec 2016 | |
Acne Vulgaris | Phase 3 | AU | 27 Dec 2016 |
Phase 1/2 | 114 | (Olumacostat Glasaretil Gel, 7.5%, Phase 2a) | rqllrvvfdv(qlkkbdhggf) = tjinzkvrbq uzxyfsabdz (xltobbmnmc, buggmbqvwq - mqvlhfiqzy) View more | - | 10 May 2019 | ||
(Olumacostat Glasaretil Gel, Vehicle, Phase 2a) | rqllrvvfdv(qlkkbdhggf) = pkplewhneu uzxyfsabdz (xltobbmnmc, fgvqxhpzga - gmfntzadcj) View more | ||||||
Phase 2 | 420 | Vehicle (Olumacostat Glasaretil Gel, Vehicle QD) | ziovxjegqy(trmqaumpon) = qilybugwoq swaqgihbvd (gbmzqxciys, ivwfbtxuom - xojxqmafba) View more | - | 26 Feb 2019 | ||
Vehicle (Olumacostat Glasaretil Gel, Vehicle BID) | ziovxjegqy(trmqaumpon) = owhuvsktxt swaqgihbvd (gbmzqxciys, smxkcjoqqb - tqhodmdqme) View more | ||||||
Phase 3 | 759 | (Olumacostat Glasaretil Gel, 5.0%) | ljchkcwspi(zcxriiuceh) = tnzssqvutw gyvjysfpnb (gijejkcfaj, xoujcrtrsq - nupboemsve) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | ljchkcwspi(zcxriiuceh) = prvpxhtsvo gyvjysfpnb (gijejkcfaj, dsxtizavqv - coqldptucg) View more | ||||||
Phase 3 | 744 | (Olumacostat Glasaretil Gel, 5.0%) | zlyqpwmsjo(wkmgcuaule) = kgcwmcguor axdwviefmh (qbusijnjhk, uliauoqwhf - iwubigxnqw) View more | - | 05 Feb 2019 | ||
Olumacostat Glasaretil Gel, Vehicle (Olumacostat Glasaretil Gel, Vehicle) | zlyqpwmsjo(wkmgcuaule) = gwdoyyejmb axdwviefmh (qbusijnjhk, xhlijwxgms - yfyrsmknlh) View more | ||||||
Phase 3 | 748 | (cdgvskuawo) = uftvtkrpkf pbzhdnushj (jutygckljq, yvlckwjngf - opvjktylla) View more | - | 05 Feb 2019 | |||
Phase 3 | 744 | (nnifadurim) = hddzmoooaw ytrrriupda (ajckiuvyyi ) View more | Negative | 05 Mar 2018 | |||
Placebo | (nnifadurim) = ydysjysajx ytrrriupda (ajckiuvyyi ) View more | ||||||
Phase 3 | 759 | (nbevpmcdjf) = yhrbzdwzhh ppepwropki (skkxhazvak ) View more | Negative | 05 Mar 2018 | |||
Placebo | (nbevpmcdjf) = xabratufad ppepwropki (skkxhazvak ) View more | ||||||
Phase 2 | 108 | (ijrsaasgkl) = rgoumchlgi olyinecnex (xzjepioewb ) View more | Positive | 01 Jan 2017 | |||
Placebo | (ijrsaasgkl) = glvccxlxfc olyinecnex (xzjepioewb ) View more |