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Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date- |
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MechanismFGFR2 antagonists |
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Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date- |
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MechanismFGFR2 antagonists |
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Inactive Indication- |
Drug Highest PhasePreclinical |
First Approval Ctry. / Loc.- |
First Approval Date- |
A Phase I, Multicenter, Open-label Study to Evaluate the Safety, Pharmacokinetics, Preliminary Efficacy of KNT-0916 in Subjects With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations
This is a Phase1, open-label, dose escalation and expansion study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of KNT-0916 in patients with unresectable or metastatic solid tumors harboring FGFR2 alterations who have failed prior systemic therapy. This study is divided into 2 parts, dose escalation part(part A), dose expansion part(partB).
/ Not yet recruitingPhase 1 评价KNT-0916片在中国健康参与者中的安全性和临床药理学特征的临床I期研究
[Translation] A Phase I clinical study evaluating the safety and clinical pharmacology of KNT-0916 tablets in healthy Chinese participants.
在中国健康参与者中评估不同类型饮食(低脂餐、高脂餐)对KNT-0916片的药代动力学(PK)特征的影响和KNT-0916片的安全性;
[Translation] To evaluate the effects of different dietary types (low-fat meals and high-fat meals) on the pharmacokinetic (PK) characteristics and safety of KNT-0916 tablets in healthy Chinese participants;
100 Clinical Results associated with KinoTeck Therapeutics Co., Ltd
0 Patents (Medical) associated with KinoTeck Therapeutics Co., Ltd
100 Deals associated with KinoTeck Therapeutics Co., Ltd
100 Translational Medicine associated with KinoTeck Therapeutics Co., Ltd