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MechanismURAT1 inhibitors |
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Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.Japan |
First Approval Date23 Jan 2020 |
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Mechanism5-HT1A receptor agonists [+2] |
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Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.Spain |
First Approval Date16 Apr 2010 |
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Drug Highest PhaseApproved |
First Approval Ctry. / Loc.United States |
First Approval Date25 Nov 1996 |
E7386与其他抗癌药物(E7080/甲磺酸仑伐替尼胶囊)联合治疗实体瘤受试者的开放研究
[Translation] An open-label study of E7386 in combination with other anticancer drugs (E7080/lenvatinib mesylate capsules) in subjects with solid tumors
主要目的
评估E7386与其他抗癌药物联合治疗的安全性和耐受性并确定推荐II期剂量(RP2D)
仅限EC剂量优化部分:确定E7386联合仑伐替尼治疗子宫内膜癌(EC)的最佳剂量
[Translation] Primary Objective
To evaluate the safety and tolerability of E7386 in combination with other anticancer drugs and determine the recommended Phase II dose (RP2D)
EC dose optimization part only: To determine the optimal dose of E7386 combined with lenvatinib for the treatment of endometrial cancer (EC)
一项在中国健康受试者中进行的Dotinurad单次和多次给药的药代动力学研究
[Translation] A single and multiple-dose pharmacokinetic study of Dotinurad in healthy Chinese subjects
主要目的 在中国健康男性和女性受试者中,评价dotinurad单次和多次口服给药后的药代动力学(PK).
[Translation] Primary Objective To evaluate the pharmacokinetics (PK) of dotinurad after single and multiple oral doses in healthy Chinese male and female subjects.
一项Dotinurad(4 mg)对比非布司他(40 mg)治疗痛风受试者的随机、多中心、双盲研究
[Translation] A randomized, multicenter, double-blind study of dotinurad (4 mg) versus febuxostat (40 mg) in subjects with gout
主要目的
在中国痛风受试者中,第24周达到血清尿酸(SUA)水平≤6.0 mg/dL的受试者比例方面,比较dotinurad 4 mg和非布司他40 mg的疗效。
[Translation] Primary objective: To compare the efficacy of dotinurad 4 mg and febuxostat 40 mg in Chinese gout subjects in terms of the proportion of subjects achieving serum uric acid (SUA) levels ≤6.0 mg/dL at week 24.
100 Clinical Results associated with Eisai China, Inc.
0 Patents (Medical) associated with Eisai China, Inc.
100 Deals associated with Eisai China, Inc.
100 Translational Medicine associated with Eisai China, Inc.