Beijing Hebikang Technology Development Co., Ltd.

The primary objective was to compare the time during which the pH of the compound sodium alginate suspension was less than 4 during the 4-hour period after administration with the corresponding placebo. The secondary objective was to determine and compare the number of occurrences and percentage of time during which the pH was less than 4 and 5 during the first hour and during the 4-hour period after administration. Other secondary objectives included comparison of the longest reflux time and DeMeester score during the 4-hour period.

The primary objective of this study was to evaluate the efficacy of sodium alginate compound suspension compared with placebo in alleviating the overall symptoms of heartburn and acid reflux in subjects with gastroesophageal reflux disease.

To evaluate the effectiveness of sodium alginate compound double-acting bilayer chewable tablets (mint flavour) compared with matching placebo in relieving GERD symptoms in patients with GERD.