A review of publications for the last 10-12 years on the HPLC anal. of multicomponent pharmaceutical formulations was presented. The peculiarities of the anal. of drug products are discussed, including applied adsorbents, mobile-phase composition, elution mode, derivatization procedure, detectors, and methods for reducing the time of anal. The use of ion-exchange, ion-pair, and enantioselective HPLC in determining the components of pharmaceutical preparations is considered.