[Translation] A randomized, double-blind, placebo-controlled, single-dose and multiple-ascending-dose study to evaluate the safety, tolerability, pharmacokinetics and food effects of oral RJ4287 tablets in healthy adult subjects.
主要目的:评价RJ4287片单次和多次口服给药在健康受试者中的安全性和耐受性。
次要目的:评价RJ4287片单次和多次口服给药在健康受试者中的药代动力学(PK)和药效动力学(PD)。 评价食物对RJ4287片药代动力学(PK)的影响。
[Translation] Primary objective: To evaluate the safety and tolerability of single and multiple oral administration of RJ4287 tablets in healthy subjects.
Secondary objective: To evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of single and multiple oral administration of RJ4287 tablets in healthy subjects. To evaluate the effect of food on the pharmacokinetics (PK) of RJ4287 tablets.