[Translation] A randomized, double-blind, placebo-controlled, multiple-dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of AP303 given orally for two weeks in patients with diabetic nephropathy and renal impairment
评估AP303多次递增剂量口服给药在糖尿病肾病伴肾功能损害的患者中的安全性和耐受性
表征AP303单次和多次递增剂量在糖尿病肾病伴肾功能损害的患者中的药代动力学(PK)
[Translation] To evaluate the safety and tolerability of AP303 in patients with diabetic nephropathy and renal impairment after multiple ascending doses of oral administration
To characterize the pharmacokinetics (PK) of AP303 in patients with diabetic nephropathy and renal impairment after single and multiple ascending doses