[Translation] A single-center phase I clinical study to evaluate the safety, efficacy, and pharmacokinetic characteristics of MBC19 in the treatment of relapsed or refractory B-cell lymphoma
1.研究MBC19治疗复发性或难治性B细胞淋巴瘤的安全性和耐受性。 2.研究MBC19的药代动力学特征。
3.探索MBC19最大耐受剂量(MTD)及推荐II期剂量(RP2D)。
4.研究MBC19治疗复发性或难治性B细胞淋巴瘤的细胞因子水平。
5.研究MBC19的免疫原性。
6.初步探索MBC19的抗肿瘤疗效。
[Translation] 1. Study the safety and tolerability of MBC19 in the treatment of relapsed or refractory B-cell lymphoma. 2. Study the pharmacokinetic characteristics of MBC19.
3. Explore the maximum tolerated dose (MTD) and recommended phase II dose (RP2D) of MBC19.
4. Study the cytokine levels of MBC19 in the treatment of relapsed or refractory B-cell lymphoma.
5. Study the immunogenicity of MBC19.
6. Preliminary exploration of the anti-tumor efficacy of MBC19.