Beijing Yikangxing Medicine Co., Ltd.

Bosentan tablets (specification: 125 mg/tablet) produced by Beijing Yikangxing Pharmaceutical Co., Ltd. were used as the test preparation, and Bosentan tablets (specification: 125 mg/tablet) produced by Actelion Pharmaceuticals Ltd. were used as the reference preparation. According to the relevant provisions of the bioequivalence test, the bioequivalence of the two preparations in healthy adult males was investigated.

Main purpose: Using Tandospirone Citrate Tablets (Specification: 10 mg/tablet) of Beijing Yikangxing Pharmaceutical Co., Ltd. as the test preparation and Tandospirone Citrate Tablets (trade name: Sediel®, specification: 10 mg/tablet) of the original research company Sumitomo Dainippon Pharma Co., Ltd. as the reference preparation, according to the relevant provisions of the bioequivalence test, the bioequivalence of the two preparations in healthy human bodies was investigated. Secondary purpose: To observe the safety of the test preparation and the reference preparation in healthy subjects.

Main research purpose: To study the oral administration of the test preparation Cefdinir Granules for Children (specification 50 mg/bag) and the reference preparation Sefdinir Fine Granules 10% in fasting and postprandial states to healthy subjects. (trade name: Cefzon®), to examine the bioequivalence of the two preparations and provide a basis for registration application. Secondary research purpose: To observe the safety of the test preparation Cefdinir Granules for Children and the reference preparation Cefzon® in healthy subjects.