Target- |
MechanismCell replacements |
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Inactive Indication- |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date- |
/ Not yet recruitingPhase 3 A Phase 3, Multicentre, Randomised, Double Blind, Placebo-controlled Study to Evaluate the Effectiveness, Safety, and Tolerability of MAG200 (an Allogeneic Adipose-derived Mesenchymal Stem Cell Preparation) Administered by Intra-articular Injection to Adult Participants With Symptomatic Osteoarthritis of the Knee.
The purpose of this study is to confirm whether MAG200 (20M or 100M) will improve pain and function of participants with osteoarthritis of the knee compared with placebo. In addition, the two strengths of MAG200 will be compared.
In this study, participants will receive a single injection of placebo or allogeneic ADMSCs (MAG200) administered by IA injection. Participants will be randomised to receive placebo, or MAG200 at a dose of 20 million cells (20M), or MAG200 at a dose of 100 million cells (100M).
It is anticipated that the study will run for approximately 48 months.
/ Not yet recruitingNot ApplicableIIT The evaluation of safety of intra-venous autologous adipose derived mesenchymal stem cell therapy in the treatment of small joint osteoarthritis. A pilot study.
/ CompletedNot Applicable Evaluation of adipose-derived mesenchymal stem cells for the treatment of chronic lower back discogenic pain - a prospective, case series pilot study
100 Clinical Results associated with Magellan Stem Cells Pty Ltd.
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