Subject of study. One of the causes of dental hyperesthesia is uncontrolled use of whitening toothpastes. The issues of diagnostics (especially in terms of interpretation of the obtained results) and treatment of hypersensitivity of hard tissues of teeth, for which various methods and preparations based on remineralization and sealing are used, do not lose their relevance. Objectives. The purpose of the study was to examine the influence of the whitening toothpastes usage on the occurrence and nature of the course of hyperesthesia of hard tissues of teeth, as well as to evaluate the effectiveness of its treatment. Materials and methods. A questionnaire survey of 162 respondents aged from 19 to 29 years was conducted, as well as further clinical examination and treatment of 72 patients suffering from hyperesthesia of hard tissues of teeth, which occurred against the background of using whitening toothpastes. To assess the intensity of hyperesthesia we used: the index of dental hyperesthesia intensity (IHI) and the NRS scale. These patients were divided into 2 clinical groups depending on the method of hyperesthesia treatment (group 1 – Gluftored; group 2 – Admira Protect). The results of the performed hyperesthesia treatment were evaluated on the 3rd, 10th days, as well as 3 months after its implementation. Results. By the 3rd day of hyperesthesia treatment, Admira Protect demonstrated greater efficacy compared to Gluftorod according to the dynamics of IHI and NRS (p < 0.05). By the end of the following week, stabilization of the above-mentioned indices and their comparable values in the groups were observed (p > 0.05). However, by the 3rd month of observation in the 1st group there was a statistically significant increase in IHI and NRS (p < 0.05). Conclusions. The use of whitening toothpastes without a dentist's prescription has a high prevalence among young adults (77.7%), which may lead to hyperesthesia of hard dental tissues. Most of the examined individuals using abrasive toothpastes had symptoms of hyperesthesia (57.1%). The study revealed high efficacy of Gluftored and Admira Protect, however, the time of desensitizing effect and stability of clinical result in the 2nd group was higher than in the 1st group (p < 0.05).

10 Feb 2025·Actual problems in dentistry

ASSESSMENT OF DENTAL PULP REGENERATIVE POTENTIAL AS THE MOST IMPORTANT ELEMENT OF PREVENTIVE ENDODONTICS PRINCIPLES REALIZATION

Author: Trigolos, Natalia ; Alekhanova, Irina ; Krajnov, Sergej ; Popova, Alexandra ; Myasoedova, Ksenia ; Yakovlev, Anatoliy ; Firsova, Irina

Subject of study. In the treatment of reversible forms of pulpitis, the principles of preventive endodontics aimed at preserving the vitality of the pulp are of great importance. For the realization of these principles, it is necessary to evaluate its regenerative potential, the verifier of which is the dynamics of transforming growth factor (TGF-β1) in gingival fluid (GF). Objectives. The purpose of the study was to optimize the assessment of tooth pulp regenerative potential in the treatment of reversible forms of pulpitis by analyzing the dynamics of TGF-β1 in GF. Materials and methods. 191 patients aged 19–29 years with reversible forms of pulpitis (K04.00 – “Pulp hyperemia” and K04.03 – “Chronic pulpitis”) were examined and treated, and were divided into 2 clinical groups: 1st – with pulp hyperemia and 2nd – with reversible form of chronic fibrous pulpitis. Each group was divided into subgroups (a, b, c), depending on the method of treatment: in subgroups 1a and 2a, a material based on calcium hydroxide was applied; in 1b and 2b, a preparation based on calcium silicate was applied; in subgroups 1c and 2c there combined the latter with laser therapy. The control group included 34 patients with intact pulp. To assess the regenerative potential of the dental pulp, the level of TGF-β1 in the GF was determined (at the initial examination, 7, 14, 21, and 30 days after the start of treatment of reversible pulpitis). Results. According to the data of the study, the combination of calcium silicate-based preparation and laser therapy demonstrated the highest clinical efficacy in comparison with calcium hydroxide-based material, harmonization of TGF-β1 activation processes in subgroups 1c and 2c came earlier (by the 7th day) (p < 0,05). At the same time, 2 patients (6.5%) of subgroup 2a were diagnosed with exacerbation of chronic fibrous pulpitis. Conclusions. Assessment of TGF-β1 concentration and its dynamics in GF allows to analyze reparative capabilities and processes occurring in the tooth pulp in pathological conditions and during various methods of conservative treatment to choose the most effective therapy.

12 Dec 2024·Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry

REACTIONS OF SYSTEMIC HEMODYNAMICS IN FOREIGN STUDENTS TO LOCAL COLD STIMULATION

Author: Sevryukova, G. ; Tovmasyan, L.

The article is devoted to the study of systemic hemodynamics in response to local cold stimulation in Indian students (n = 68). Objective: to research of systemic circulation in response to local cold stimulation in foreign students in the process of their adaptation to the sharply continental climate of the Volgograd region. Systemic hemodynamics was assessed at rest, in response to local cold stimulation and during the recovery period at 1, 3 and 5 minutes. Blood pressure (systolic, diastolic), heart rate, pulse pressure, average hemodynamic pressure, and cardiovascular endurance coefficient were recorded. The type of systemic circulation was determined by the cardiac index (hypokinetic, eukinetic, hyperkinetic). As a result of differentiation by cardiac index, it was revealed that the eukinetic type of blood circulation was observed in a larger number of Indian students – 44,9 %; hypo- and hyperkinetic – 25,3 %, 29,8 %, respectively. In response to the cold test, all examined students showed an increase in heart rate; the most pronounced increase in the indicator was found in students with a hypokinetic type of blood circulation. The reactions of students with a hyperkinetic type of blood circulation were characterized by their instability to local cold stimulation: by the 1st minute of the recovery period the heart rate decreased by 9,5 %, by the 3rd minute – the heart rate increased by 5,7 %, and by the 5th minute it decreased again. In students with the hyperkinetic type, there was a significant increase in diastolic pressure and a sharp decrease in pulse pressure at the peak of cold stimulation and then a sharp increase at 1 minute of the recovery period. Unfavorable criteria for adaptation to cold stimulation include: decreased endurance of the cardiovascular system, unstable systemic hemodynamics and inadequate amplitude of pulse pressure fluctuations during the recovery period, and a hyperkinetic type of systemic circulation. Favorable criteria for the adaptive reaction of the body of foreign students in response to local cold stimulation are: a decrease in the amplitude of deviation of the studied parameters and the time of their recovery. This must be used when assessing the adaptive reactions of the cardiovascular system in foreign students in the process of adaptation to the climatic and geographical conditions of their living and studying environment.

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