Delving into the Latest Updates on M.S. Ramaiah University of Applied Sciences with Synapse

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Endocrinology and Metabolic Disease

Infectious Diseases

Urogenital Diseases

Small molecule drug

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Endocrinology and Metabolic Disease	1
Infectious Diseases	1

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Small molecule drug	1

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NF-κB x TLR4	1

The demand for advanced materials in anti-counterfeiting drives research into nanophosphors.Building on prior work [1] that identified strong reddish-orange luminescence in (Y₁-x)₂WO₆:xEu³⁺ nanophosphors for xEu³⁺=0.07, this study explores the structural, optical and magnetic properties (Y₁-x-y)₂WO₆:xEu3+:yBi³⁺ (xEu³⁺ = 0.07; yBi³⁺ = 0.01, 0.03, 0.05) nanophosphors synthesized via the solution combustion technique.The nanophosphors exhibit a monoclinic structure with wire-like morphol.Raman and FTIR spectroscopy reveal bonding details, while UV-vis spectra indicate strong UV absorbance with Bi³⁺ incorporation.Photoluminescence anal. identifies the xEu³⁺ = 0.07:yBi³⁺ = 0.03 composition as optimal for stable dual luminescence, exhibiting reddish-orange and bright pink emission under 345 nm and 365 nm excitation, resp.Addnl., the phosphors display soft magnetic properties.Phys. and chem. stability tests further confirm the composition potential as dual fluorescent magnetic pigment for anti-counterfeiting applications, offering a visually distinctive and robust security feature.The combined optical and magnetic characteristics position the (Y₁-x-y)₂WO₆:0.07Eu³⁺:0.03Bi³⁺ nanophosphor as a promising pigment for security inks in anticounterfeit applications.

01 Jun 2025·Optics Communications

Design, simulation, and comparison of optofluidics & sensing schemes for integrated optic biosensors

Author: Chaitra Shri, K. ; Malathi, S.

Integrated Optic waveguide-based sensors are promising solutions for various applications, notably in the label-free detection of chem. and biol. substances.For optimal sensitivity, the guided mode should interact with biomaterial.In this research article, we have considered Hollow-core waveguides and Strip waveguide-based biosensors.Hollow-core waveguides are analyzed as optofluidic devices in which bio-analytes form the core.Strip waveguide - Silicon on Insulator (SOI) has been considered for simulation purposes.Bulk sensing and Surface sensing scheme mechanisms were used to study the variations when bio analyte was encountered with waveguide material.In this article, we modelled, simulated, and analyzed two types of waveguides viz., Optofluidic channel with biomaterial as core, bulk sensing with biomaterial as clad covering the Silicon strip waveguide, and surface sensing with biomaterial covering the surface of the waveguide.Optofluidic channel with sensitivity in refractive index unit (RIU), the range of 2.4*10 ^-2/RIU to 2.8*10 ^-2/RIU; Bulk sensing sensitivity in the range of 2.5*10 ^-1/RIU to 3.7*10 ^-1/RIU; Surface sensing sensitivity in the range of 1.96*10 ^-2/RIU to 2.9*10 ^-3/RIU for different biomaterials.The main reason for selecting these ranges is that they represent practical and achievable values based on the phys. interaction between light and biomaterials.These ranges also consider the technol. constraints and the objectives of various biosensing applications.The novelty of the optofluidic scheme emanates from the ability to integrate fluidic and photonic elements to allow label-free detection due to the compact designs and high sensitivity.The optofluidic scheme offers advantages over bulk sensing (which relies on external cladding materials) and surface sensing (which only probes the interface) by providing volumetric sensing capabilities.We observed and analyzed results to derive design guidelines.Our findings assist in choosing an appropriate platform and optimizing sensitivity by the effective refractive index for the given bio application.

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Pipeline

Pipeline Snapshot as of 12 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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