Metal-organic frameworks (MOFs) have arisen as a promising category of substances for sensing applications because of their unique structural features and tailorable characteristics.In this study, functionalization of UiO-66-NH2 with 4-chloro-3-formylcoumarin was completed to enhance the fluorescence properties and selective binding interactions.So, the florescence response of UiO-66-N-ChloroCoumarin (UiO-66-N-CC) towards various ions was studied and the obtained results represented high selectivity for Al3+ and F- ions in EtOH.The UiO-66-N-CC exhibited a linear correlation for Al3+ ions from 10 to 940 μL, with detection limit of 8.79 x 10-5 M and for F- ions, from 10 to 100 μL, with detection limit of 3.39 x 10-5 M.Addnl., the influence of potential interfering ions, including Ag+, K+, Pb2+, Hg2+, Cd2+, Ni2+, Ca2+, Cu2+, Mg2+, Mn2+, Co2+, Zn2+, Cr3+ for Al3+ and Br-, Cl-, I-, F-, CN-, SCN-, OH-, NO-2, CH3COO-, HSO-3, SO2-4, Cr2O2-7, HPO2-4, CO2-3 for F-, was investigated, demonstrating minimal effects on the fluorescence emission, conforming the selectivity of the method.The gaseous phase d. functional theory (DFT) calculation was performed by B3LYP/6-311 g (d,p)/def2-TZVP computational methodol. for the ground state of UiO-66-N-CC and UiO-66-N-CC+Al3+complex.The reactivity, stability, and mechanism of the interaction between UiO-66-N-CC and Al3+ ions were investigated by DFT calculations like geometry optimization, MEP surface, and MO theory.