Delving into the Latest Updates on Lanzhou Lansheng Blood Products Co., Ltd. with Synapse

Overview

Basic Info

Introduction

Lanzhou Lansheng Blood Products Co., Ltd. is a pharmaceutical company based in China that produces and distributes various pharmaceutical products. The company is part of Beijing Tiantan Biological Products Corp. Ltd. and was previously owned by China National Pharmaceutical Group Co., Ltd. However, in January 2018, the company was acquired by Chengdu Rongsheng Pharmaceutical Co., Ltd. for a sum of $89.85 million.

Tags

Congenital Disorders

Hemic and Lymphatic Diseases

Other Diseases

Non-recombinant coagulation factor

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Hemic and Lymphatic Diseases	1

Top 5 Drug Type	Count

Non-recombinant coagulation factor	1

Top 5 Target	Count

F10 x factor IX x factor VII x thrombin	1

Objective To establish gas chromatog. for the determination of tri-Bu phosphate (TBP) residues in human prothrombin complex and then verify it.Methods Acid modified polyethylene glycol (PEG) (20 M) capillary column was used with n-hexane as solvent.The chromatog. parameters were as follows: gasification chamber temperature at 220°C, column temperature at 155°C, detector temperature at 220°C, column flow rate at 2.0 mL/min, carrier gas as N2, detector as FID, and collection time for 10 min.The accuracy, repeatability, linearity, specificity, intermediate precision, detection limit, quant. limit, range and durability were verified.Results The verification results showed that the method had good specificity.The linear regression correlation coefficient of standard curve was 0.99990.The recovery rate were 98.4%, 97.5%and 95.7%when the concentration at 50%, 100% (30 μg/mL) and 150%, resp., with an average recovery of 97.2% and a relative deviation of 2.15%.When the concentration was 100%, the repeatability was 2.08%, and the relative deviation of intermediate precision was 1.63%.The detection limit was 0.255 μg/mL, and the quant. limit was 0.511 μg/mL.After changing capillary chromatog. columns with different batch numbers but the same types and manufacturer, the applicability test of the system met the requirements, and the method had good durability.Conclusion This method can be used for the determination of TBP residues of human prothrombin complex in laboratory

100 Deals associated with Lanzhou Lansheng Blood Products Co., Ltd.

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100 Translational Medicine associated with Lanzhou Lansheng Blood Products Co., Ltd.

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Pipeline

Pipeline Snapshot as of 26 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Approved

1

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